Evidence map›Paper›PMID 31370274›Full record

ArticleMolecules (Basel, Switzerland)2019

Synthesis and In Vitro Evaluation of 8-Pyridinyl-Substituted Benzo[

Rien Ritawidya, Friedrich-Alexander Ludwig, Detlef Briel, Peter Brust, Matthias Scheunemann

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Radiosynthesis and Preclinical Evaluation of anPharmaceuticals (Basel, Switzerland) · 2022
    Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Rien RitawidyaDepartment of Neuroradiopharmaceuticals, Institute of Radiopharmaceuticals Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf, Leipzig 04318, Germany. r.ritawidya@hzdr.de.
Friedrich-Alexander LudwigDepartment of Neuroradiopharmaceuticals, Institute of Radiopharmaceuticals Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf, Leipzig 04318, Germany.
Detlef BrielPharmaceutical/Medicinal Chemistry, Institute of Pharmacy, Faculty of Medicine, Leipzig University, Brüderstraße 34, Leipzig 04103, Germany.
Peter BrustDepartment of Neuroradiopharmaceuticals, Institute of Radiopharmaceuticals Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf, Leipzig 04318, Germany.
Matthias ScheunemannDepartment of Neuroradiopharmaceuticals, Institute of Radiopharmaceuticals Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf, Leipzig 04318, Germany. rienrita@batan.go.id.
Helmholtz-Zentrum Dresden-Rossendorf · DELeipzig University · DE

Funding

Deutsche Forschungsgemeinschaft SCHE 1825/3-1Indonesia Ministry of Research and Technology-Program for Research and Innovation in Science and Technology Project (RISET-Pro) World Bank Loan No: 8245-ID
6 · The paper itself

Abstract

Phosphodiesterase 2A (PDE2A) is highly expressed in distinct areas of the brain, which are known to be related to neuropsychiatric diseases. The development of suitable PDE2A tracers for Positron Emission Tomography (PET) would permit the

Indexed as

AnimalsBrainCyclic Nucleotide Phosphodiesterases, Type 2HumansLigandsMicePositron-Emission TomographyRadiopharmaceuticalsTriazinesCyclic Nucleotide Phosphodiesterases, Type 2LigandsRadiopharmaceuticalsTriazinesBenzoimidazotriazine (BIT)fluorinatedMouse Liver Microsomes (MLM)Phosphodiesterase 2A (PDE2A)Positron Emission Tomography (PET)

Identifiers

PMID31370274
PMCPMC6696243
OpenAlexW2966382801

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.