ArticleInternational journal of molecular sciences2019
Endometrial Stromal Cells Circulate in the Bloodstream of Women with Endometriosis: A Pilot Study.
Article in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
9 citing papers in PubMed, 11 citations in OpenAlex.
- A 3D PDMS Scaffold Microchip Platform for Non-Invasive Detection of Circulating Endometrial Cells: Revolutionizing Endometriosis Diagnosis.Current medical science · 2026Article
- The Molecular and Cellular Mechanisms of Endometriosis: From Basic Pathophysiology to Clinical Implications.International journal of molecular sciences · 2025Review
- Detection of Circulating Tumor Cell-Related Markers in Gynecologic Cancer Using Microfluidic Devices: A Pilot Study.International journal of molecular sciences · 2023Article
- Differential Expression and Bioinformatics Analysis of tRF/tiRNA in Endometriosis Patients.BioMed research international · 2022Article
- Mesenchymal Stromal Cells Isolated from Ectopic but Not Eutopic Endometrium Display Pronounced Immunomodulatory Activity In Vitro.Biomedicines · 2021Article
- Clinico-pathological assessment of surgically removed abdominal wall endometriomas following cesarean section.Annals of medicine and surgery (2012) · 2021Article
- CD200 and CD200R Expression on Peripheral Blood Lymphocytes and Serum CD200 Concentration as a New Marker of Endometriosis.Journal of clinical medicine · 2020Article
- Epithelial-Mesenchymal Transition in Endometriosis-When Does It Happen?Journal of clinical medicine · 2020Review
- Circulating Endometrial Cells: A New Source of Information on Endometriosis Dynamics.Journal of clinical medicine · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
Abstract
Endometriosis is characterized by the presence of endometrial tissue outside the uterus. While endometriotic tissue is commonly localized in the pelvic cavity, it can also be found in distant sites, including the brain. The origin and pathophysiology of tissue migration is poorly understood; retrograde menstruation is thought to be the cause, although the presence of endometrium at distant sites is not explained by this hypothesis. To determine whether dissemination occurs via the bloodstream in women with endometriosis, we analyzed circulating blood for the presence of endometrial cells. Circulating endometrial stromal cells were identified only in women with endometriosis but not in controls, while endometrial epithelial cells were not identified in the circulation of either group. Our results support the hypothesis that endometrial stromal cells may migrate through circulation and promote the pathophysiology of endometriosis. The detection of these cells in circulation creates avenues for the development of less invasive diagnostic tools for the disease, and opens possibilities for further study of the origin of endometriosis.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.