Evidence map›Paper›PMID 31370181›Full record

ArticleInternational journal of molecular sciences2019

Exploring the N-Glycosylation Profile of Glycoprotein B from Human Cytomegalovirus Expressed in CHO and

Nicolas Smargiasso, Joseph Nader, Stéphane Rioux, Gabriel Mazzucchelli, Marc Boutry, Edwin De Pauw, François Chaumont, Catherine Navarre

Open access · goldAbstract readComparative Study
In one paragraph

Article in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Structure-based design of a soluble human cytomegalovirus glycoprotein B antigen stabilized in a prefusion-like conformation.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  3. Article
  4. The advent of plant cells in bioreactors.Frontiers in plant science · 2023
    Review
  5. Review
  6. Review
  7. Inactivation ofFrontiers in plant science · 2021
    Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Nicolas SmargiassoMass Spectrometry Laboratory-MolSys, GIGA Proteomics Facility, University of Liège, 4000 Liège, Belgium.
Joseph NaderLouvain Institute for Biomolecular Science and Technology, UCLouvain, 1348 Louvain-la-Neuve, Belgium.
Stéphane RiouxGlaxoSmithKline Vaccines, 1330 Rixensart, Belgium.
Gabriel MazzucchelliMass Spectrometry Laboratory-MolSys, GIGA Proteomics Facility, University of Liège, 4000 Liège, Belgium.
Marc BoutryLouvain Institute for Biomolecular Science and Technology, UCLouvain, 1348 Louvain-la-Neuve, Belgium.
Edwin De PauwMass Spectrometry Laboratory-MolSys, GIGA Proteomics Facility, University of Liège, 4000 Liège, Belgium.
François ChaumontLouvain Institute for Biomolecular Science and Technology, UCLouvain, 1348 Louvain-la-Neuve, Belgium. francois.chaumont@uclouvain.be.ORCID 0000-0003-0155-7778
Catherine NavarreLouvain Institute for Biomolecular Science and Technology, UCLouvain, 1348 Louvain-la-Neuve, Belgium.
UCLouvain · BEUniversity of Liège · BEGlaxoSmithKline (Belgium) · BE

Funding

Service Public de Wallonie 1318062
6 · The paper itself

Abstract

The ability to control the glycosylation pattern of recombinant viral glycoproteins represents a major prerequisite before their use as vaccines. The aim of this study consisted of expressing the large soluble ectodomain of glycoprotein B (gB) from Human Cytomegalovirus (HMCV) in

Indexed as

Ammonium SulfateAnimalsCarbohydrate SequenceChemical PrecipitationCHO CellsChromatography, GelCricetulusGalactoseGene ExpressionGlycosylationHumansN-Acetylneuraminic AcidNicotianaPeptide FragmentsPlant CellsPolysaccharidesAmmonium SulfateGalactoseglycoprotein B, SimplexvirusN-Acetylneuraminic AcidPeptide FragmentsPolysaccharidesRecombinant ProteinsViral Envelope Proteinscytomegalovirusglycoprotein Bmass spectrometryN-glycosylationplant cell suspension culture

Identifiers

PMID31370181
PMCPMC6696289
OpenAlexW2966719073

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.