Evidence map›Paper›PMID 31370168›Full record

ReviewJournal of clinical medicine2019

Periodontitis: A Multifaceted Disease of Tooth-Supporting Tissues.

Eija Könönen, Mervi Gursoy, Ulvi Kahraman Gursoy

3 registry-linked trialsOpen access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Journal of clinical medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 431 papers, 10 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
431citing papers in PubMed, 10 pooled it
53.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06486012 narecruitingnot on this mapstarted 2025, after this paper: background citation

Regular Use of Antibacterial Photodynamic Therapy in the Management and Prevention of Periodontitis Symptoms in Diabetic Patients - Special Attention to Diabetic Balance and Metabolism

TypeinterventionalSponsorWellbeing Services County of PirkanmaaRan2025 to 2028Enrolled150ConditionsDiabetes Mellitus, Type 2, Pre-diabetes, Periodontal Diseases, PeriodontitisArmsLumoral Treatment, Standard oral hygiene
NCT06962878 nanot yet recruitingnot on this mapstarted 2025, after this paper: background citation

Assessment of Bone Volume Changes in Immediate Implant Placement Using Allograft Versus Xenograft in Mandibular Molars: Randomized Clinical Trial

TypeinterventionalSponsorCairo UniversityRan2025 to 2026Enrolled20ConditionsBone Volume, Immediate Implant With Bone GraftArmsXenograft, Allograft
NCT07405268 active not recruitingnot on this mapstarted 2026, after this paper: background citation

The Effect of Levodopa-Benserazide Combination on Periodontal Status in Patients With Parkinson's Disease: A Cross-Sectional Study

Typeobservational_patient_registrySponsorSaglik Bilimleri UniversitesiRan2026 to 2026Enrolled136ConditionsParkinson Disease (PD), Periodontitis, Periodontal Diseases
3 · Its place in the literature

Who cites it

431 citing papers in PubMed, 10 syntheses or guidelines pooled it, 802 citations in OpenAlex.

  1. Efficacy of adjunct Nd-YAG laser (1064 nm) to non-surgical periodontal therapy: a systematic review and meta-analysis of randomized controlled trials.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2026
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371 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Eija KönönenDepartment of Periodontology, Institute of Dentistry, University of Turku, 20520 Turku, Finland. eija.kononen@utu.fi.
Mervi GursoyDepartment of Periodontology, Institute of Dentistry, University of Turku, 20520 Turku, Finland.
Ulvi Kahraman GursoyDepartment of Periodontology, Institute of Dentistry, University of Turku, 20520 Turku, Finland.ORCID 0000-0002-1225-5751
University of Turku · FI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Periodontitis is an infection-driven inflammatory disease in which the composition of biofilms plays a significant role. Dental plaque accumulation at the gingival margin initiates an inflammatory response that, in turn, causes microbial alterations and may lead to drastic consequences in the periodontium of susceptible individuals. Chronic inflammation affects the gingiva and can proceed to periodontitis, which characteristically results in irreversible loss of attachment and alveolar bone. Periodontitis appears typically in adult-aged populations, but young individuals can also experience it and its harmful outcome. Advanced disease is the major cause of tooth loss in adults. In addition, periodontitis is associated with many chronic diseases and conditions affecting general health.

Indexed as

alveolar bone lossbacteriabiofilmgingivaimmunityinflammationperiodontal diseasesmoking

Identifiers

PMID31370168
PMCPMC6723779
OpenAlexW2964512159

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.