Evidence map›Paper›PMID 31370100›Full record

SynthesisActa obstetricia et gynecologica Scandinavica2020

The impact of uterine artery embolization on ovarian reserve: A systematic review and meta-analysis.

Tarek El Shamy, Saad A K Amer, Ahmed A Mohamed, Cathryn James, Kannamannadiar Jayaprakasan

Open access · bronzeAbstract readMeta-AnalysisSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Acta obstetricia et gynecologica Scandinavica, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
8.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 82 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 2 countries.

Tarek El ShamyDerby Fertility Unit, University Hospitals of Derby and Burton NHS Foundation Trust, Derby, UK.
Saad A K AmerDerby Fertility Unit, University Hospitals of Derby and Burton NHS Foundation Trust, Derby, UK.ORCID 0000-0001-8321-1302
Ahmed A MohamedDepartment of Obstetrics and Gynecology, Faculty of Medicine, Assiut University, Assiut, Egypt.
Cathryn JamesLibrary & Knowledge Service, University Hospitals of Derby and Burton NHS Foundation Trust, Derby, UK.
Kannamannadiar JayaprakasanDerby Fertility Unit, University Hospitals of Derby and Burton NHS Foundation Trust, Derby, UK.
University of Nottingham · GBAssiut University · EGUniversity Hospitals of Derby and Burton NHS Foundation Trust · GBWest Middlesex University Hospital · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionUterine artery embolization (UAE) has been gaining increasing popularity as an effective and minimally invasive treatment for uterine fibroids. However, there has been growing concern over the risk of unintended embolization of the utero-ovarian circulation, leading to reduction of ovarian blood supply with subsequent impairment of ovarian reserve. The purpose of this study was to investigate the impact of UAE on circulating anti-Müllerian hormone (AMH) and other markers of ovarian reserve. MATERIAL AND

methodsThis meta-analysis included all published cohort, cross-sectional and case-control studies, as well as randomized trials that investigated the impact of UAE on circulating AMH. Data sources included MEDLINE, EMBASE, Dynamed Plus, ScienceDirect, TRIP database, ClinicalTrials.gov and the Cochrane Library from January 2000 to June 2019. All identified articles were screened, and articles were selected based on the inclusion and exclusion criteria. AMH and other data were extracted from the eligible articles and entered into RevMan software to calculate the weighted mean difference between pre- and post-embolization values. PROSPERO registration number: CRD42017082615.

resultsThis review included 3 cohort and 3 case-control studies (n = 353). The duration of follow up after UAE ranged between 3 and 12 months. Overall pooled analysis of all studies showed no significant effect of UAE on serum AMH levels (weighted mean difference -0.58 ng/mL; 95% CI -1.5 to 0.36, I

conclusionsUterine artery embolization for uterine fibroids does not seem to affect ovarian reserve as measured by serum concentrations of AMH and FSH.

Indexed as

Ovarian ReserveUterine Artery EmbolizationAdultAnti-Mullerian HormoneBiomarkersFemaleFollicle Stimulating HormoneHumansLeiomyomaUterine NeoplasmsAnti-Mullerian HormoneBiomarkersFollicle Stimulating Hormoneanti-Müllerian hormoneantral follicle countfollicle-stimulating hormoneovarian reserveuterine artery embolization

Identifiers

PMID31370100
OpenAlexW2966047758

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.