ArticleThe American journal of medicine2020
The Impact of Substance Abuse on Heart Failure Hospitalizations.
Article in The American journal of medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
33 citing papers in PubMed, 73 citations in OpenAlex.
- DASH-HF Study: A Pragmatic Quality Improvement Randomized Implementation Trial for Patients With Heart Failure With Reduced Ejection Fraction.Circulation. Heart failure · 2023Trial
- Benefits and Risks of Moderate Alcohol Consumption on Cardiovascular Disease: Current Findings and Controversies.Nutrients · 2019Trial
- Substance Use Disorder in a National Heart Failure Cohort: Risk for Hospital Readmission and Mortality.Journal of clinical medicine · 2026Article
- The Concept of Psychologically Informed Heart Transplantation Care.Journal of clinical medicine · 2026Review
- Prevalence and Impact of Substance Use on Hospitalization and Post-Discharge Outcomes in Individuals with Congestive Heart Failure: Findings from a Safety-Net Hospital.International journal of environmental research and public health · 2025Article
- Time to Death by Suicide in an Epidemiological Sample of Veterans With an Inpatient Hospitalization for Heart Failure.The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry · 2025Article
- The Gender Gap in Life Expectancy in the United States and Deaths of Despair: Trends from 1979 to 2022.Population and development review · 2025Article
- Association of substance use with stroke in heart failure by community socioeconomic distress.Drug and alcohol dependence · 2025Article
- Microbiome-derived metabolites in substance use disorders: Mechanisms and implications.Annals of the New York Academy of Sciences · 2025Review
- Pervasive stagnation: flat and increasing cardiovascular disease mortality rates after 2010 across US states and counties.American journal of epidemiology · 2025Article
- Shifting Cohort Patterns in the Use of Drugs with Elevated Overdose Risk in the United States.Social problems · 2025Article
- Article
- Role of Cardiovascular Deaths on Changes in the Longevity Gap Between U.S. and Other Countries.American journal of preventive medicine · 2025Observational
- Supervised machine learning including environmental factors to predict in-hospital outcomes in acute heart failure patients.European heart journal. Digital health · 2025Article
- Nutritional and Nutraceutical Support to the Failing Myocardium: A Possible Way of Potentiating the Current Treatment of Heart Failure.International journal of molecular sciences · 2024Review
- The impact of medication-assisted treatment for opioid use disorder on congestive heart failure outcomes.American heart journal plus : cardiology research and practice · 2024Article
- Changes in Healthcare Spending Attributable to High Deductible Health Plan Offer Among Enrollees with Comorbid Substance Use Disorder and Cardiovascular Disease.Journal of general internal medicine · 2024Article
- Cardiomyopathy-Associated Hospital Admissions Among Methamphetamine Users: Geographical and Social Disparities.JACC. Advances · 2024Article
- Predictors of All-Cause 30-Day Readmissions in Patients with Heart Failure at an Urban Safety Net Hospital: The Importance of Social Determinants of Health and Mental Health.American journal of medicine open · 2023Article
- Association of Psychosocial Risk Factors and Outcomes in Heart Failure: Does COVID-19 Affect Outcomes?Current problems in cardiology · 2023Review
Corrections and comments
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Authors and funding
10 authors at 1 institution in 1 country.
Funding
Abstract
backgroundThe burden of substance abuse among patients with heart failure and its association with subsequent emergency department visits and hospital admissions are poorly characterized.
methodsWe evaluated the medical records of patients with a diagnosis of heart failure treated at the University of California-San Diego from 2005 to 2016. We identified substance abuse via diagnosis codes or urine drug screens. We used Poisson regression to evaluate the incidence rate ratios (IRR) of substance abuse for emergency department visits or hospitalizations with a primary diagnosis of heart failure, adjusted for age, sex, race, medical insurance status, and medical diagnoses.
resultsWe identified 11,268 patients with heart failure and 15,909 hospital encounters for heart failure over 49,712 person-years of follow-up. Substance abuse was diagnosed in 15.2% of patients. Disorders such as methamphetamine abuse (prevalence 5.2%, IRR 1.96, 95% confidence interval [CI] 1.85-2.07), opioid use and abuse (8.2%, IRR 1.54, 95% CI 1.47-1.61), and alcohol abuse (4.5%, IRR 1.51, 95% CI 1.42-1.60) were associated with a greater number of hospital encounters for heart failure, with associations that were comparable to diagnoses such as atrial fibrillation (37%, IRR 1.78, 95% CI 1.73-1.84), ischemic heart disease (24%, IRR 1.67, 95% CI 1.62-1.73), and chronic kidney disease (26%, IRR 1.57, 95% CI 1.51-1.62).
conclusionsAlthough less prevalent than common medical comorbidities in patients with heart failure, substance-abuse disorders are significant sources of morbidity that are independently associated with emergency department visits and hospitalizations for heart failure. Greater recognition and treatment of substance abuse may improve outcomes among patients with heart failure.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.