Evidence map›Paper›PMID 31369708›Full record

ArticleNano letters2019

Substrate Stiffness-Dependent Carbon Nanotube-Induced Lung Fibrogenesis.

Kai Wang, Lin Shi, Will Linthicum, Kun Man, Xiaoqing He, Qi Wen, Liying Wang Rojanasakul, Yon Rojanasakul, Yong Yang

Abstract read
In one paragraph

Article in Nano letters, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.1field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 28 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Review
  8. Microphysiological Systems: Design, Fabrication, and Applications.ACS biomaterials science & engineering · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Kai WangDepartment of Biomedical Engineering , University of North Texas , Denton , Texas 76207 , United States.ORCID 0000-0001-8447-6177
Lin ShiDepartment of Biomedical Engineering , University of North Texas , Denton , Texas 76207 , United States.
Will LinthicumDepartment of Biomedical Engineering , Worcester Polytechnic Institute , Worcester , Massachusetts 01609 , United States.
Kun ManDepartment of Biomedical Engineering , University of North Texas , Denton , Texas 76207 , United States.
Xiaoqing HeDepartment of Pharmaceutical Sciences , West Virginia University , Morgantown , West Virginia 26506 , United States.
Qi WenDepartment of Biomedical Engineering , Worcester Polytechnic Institute , Worcester , Massachusetts 01609 , United States.
Liying Wang RojanasakulAllergy and Clinical Immunology Branch , National Institute for Occupational Safety and Health , Morgantown , West Virginia 26505 , United States.
Yon RojanasakulDepartment of Pharmaceutical Sciences , West Virginia University , Morgantown , West Virginia 26506 , United States.
Yong YangDepartment of Biomedical Engineering , University of North Texas , Denton , Texas 76207 , United States.ORCID 0000-0003-4305-8029
University of North Texas · USWest Virginia University · USWorcester Polytechnic Institute · USNational Institute for Occupational Safety and Health · US

Funding

Nanoparticle Fibrogenicity and Fibroblast Stem-Like CellsR01EB018857 · NIBIB · WEST VIRGINIA UNIVERSITY · PI ROJANASAKUL, YON · 2016 to 2019
$1.3M
Biomimetic Alveolar Interstitium Model for Investigation of Nanomaterials-induced FibrogenesisR15GM122953 · NIGMS · WEST VIRGINIA UNIVERSITY · PI YANG, YONG · 2016 to 2016
$431k
Intramural CDC HHS CC999999NIBIB NIH HHS R01 EB018857NIGMS NIH HHS R15 GM122953
6 · The paper itself

Abstract

Most living tissues exhibit the specific stiffness, which has been known to have profound influence on cell behaviors, yet how the stiffness affects cellular responses to engineered nanomaterials has not been elucidated. Particularly, discrepancies exist between

Indexed as

Cell LineCell MovementCollagen Type IElasticityFibroblastsFocal Adhesion Protein-Tyrosine KinasesHumansLungNanotubes, CarbonPulmonary FibrosisReactive Oxygen SpeciesCollagen Type IFocal Adhesion Protein-Tyrosine KinasesNanotubes, CarbonReactive Oxygen Speciescarbon nanotubesfocal adhesion kinaseintracellular tensionlung fibrogenesisnanotoxicitystiffness

Identifiers

PMID31369708
PMCPMC6724206
OpenAlexW2966107805

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.