ArticlePloS one2019
Microbiota of newborn calves and their mothers reveals possible transfer routes for newborn calves' gastrointestinal microbiota.
Article in PloS one, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 61 papers.
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Who cites it
61 citing papers in PubMed.
- Bidirectional regulation of gut microbiota and young ruminant host: implications for intestinal development and mucosal immunity.Journal of animal science and biotechnology · 2026Review
- Maternal Microbial Reservoirs Are Associated with Early Bacterial and Archaeal Community Assembly in Neonatal Hu Lambs.Animals : an open access journal from MDPI · 2026Article
- Assessing the Effects of Farm Management Systems and Diarrhea on Gut Microbiota and Metabolites in Dairy Calves in Indonesia.Animals : an open access journal from MDPI · 2026Article
- Harnessing the early-life gut microbiome for sustainable ruminant production.Animal microbiome · 2026Review
- Unraveling the dynamic changes in the intestinal microbiome: impacts on pre-weaning calf health and productivity.Journal of animal science and biotechnology · 2026Review
- Potential roles of colostrum microbiota in shaping calf gut microbiota and colostrum metabolites.JDS communications · 2026Article
- Fecal microbiota succession in dairy calves is driven by age and modestly influenced by colostrum source.Scientific reports · 2026Article
- Microbial colonisation of the neonatal beef calf gastrointestinal tract: limited influence of birth delivery method across five anatomical regions.Frontiers in microbiology · 2026Article
- Exploring colostrum microbiota and its influence on early calf gut microbiota development using full-length 16S rRNA gene metabarcoding.Scientific reports · 2025Article
- Lactiplantibacillus plantarum promotes lactoferrin synthesis and secretion in bovine mammary epithelial cells through STAT3 and AP-1 transcription factor pathways.In vitro cellular & developmental biology. Animal · 2025Article
- Effect of conventional grain-fed and grass-fed feeding systems on fecal microbiota and shiga toxin-producing Escherichia coli in beef cattle.BMC microbiology · 2025Article
- Impacts of prenatal nutrition on metabolic pathways in beef cattle: an integrative approach using metabolomics and metagenomics.BMC genomics · 2025Article
- Physiological and Microbial Community Dynamics in Does During Mid-Gestation to Lactation and Their Impact on the Growth, Immune Function, and Microbiome Transmission of Offspring Kids.Animals : an open access journal from MDPI · 2025Article
- Characterisation of the bacterial and archaeal microbiota in fresh colostrum collected from a single, spring-calving dairy herd.PloS one · 2025Article
- Age-stratified gut microbial changes in diarrheal calves: insights from 16S rRNA sequencing across early development.Frontiers in microbiology · 2025Article
- Research of antimicrobial resistance and its associated genes distribution inFrontiers in veterinary science · 2025Article
- The dynamic distribution of the rectal microbiota in Holstein dairy calves provides a framework for understanding early-life gut health.Animal nutrition (Zhongguo xu mu shou yi xue hui) · 2024Article
- Maternal Transmission of Rotavirus to Calves and Comparison of Colostrum and Fecal Microbiota in Holstein and Hanwoo Cattle.Veterinary sciences · 2024Article
- Vertical transfer of gut microbiota from dam to neonate calf in the early of life.Scientific reports · 2024Article
- Development of the Intestinal Microbiota of Dairy Calves and Changes Associated withMicroorganisms · 2024Article
1 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The intestinal microbiota of newborns plays an important role in the development of immunity and metabolism. In livestock animals, knowledge of the intestinal microbiota is essential not only to prevent diseases but also to optimize weight gain and performance. The aim of our study was to examine faecal samples repeatedly within the first two days of life using 16S rRNA gene High Throughput Sequencing. Additionally, samples from the mouths of the calves and the vaginas, colostrum, and faeces of the dams were included to evaluate possible sources of the calf faecal microbiota. The calf faecal microbiota was highly variable during the first 48 hours post natum (p.n.). Significant changes were found in species diversity and richness, in copy numbers evaluated by qPCR and in predominant bacteria over time. The most pronounced changes occurred between 6 and 24 hours p.n. All calf faecal samples were dominated by Operational Taxonomic Units (OTUs) belonging to the family Enterobacteriaceae. Cow faecal samples showed significantly higher species richness, diversity, number of observed OTUs, and copy numbers compared to all other samples. OTUs belonging to the family Ruminococcaceae were most abundant in cow faecal and vaginal samples. Colostrum was dominated by Enhydrobacter affiliated OTUs. To identify possible inoculation routes for the calf microbiota, we analysed OTU sharing between samples. The calf microbiota during the first two days of life was clearly distinct from the dam's faecal microbiota. Furthermore, colostrum microbiota clearly differed from calf and cow faecal microbiota and thus most likely does not play an important role as inoculation source for calf microbiota during the first two days of life. In contrast, the cow vaginal and the calf faecal microbiota were more similar, suggesting that some of the calf faecal microbiota may derive from inoculation from the birth canal during birth.
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