Evidence map›Paper›PMID 31369292›Full record

ArticleAmerican journal of physiology. Gastrointestinal and liver physiology2019

Tamoxifen-induced, intestinal-specific deletion of

Subrata Sabui, Jonathan Skupsky, Rubina Kapadia, Kyle Cogburn, Nils W Lambrecht, Anshu Agrawal, Hamid M Said

Abstract read
In one paragraph

Article in American journal of physiology. Gastrointestinal and liver physiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 26 citations in OpenAlex.

  1. Phenotypic switching of gastrointestinal smooth muscle cells and the regulatory role of macrophages: a literature review.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2026
    Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Review
  8. Biotin Homeostasis and Human Disorders: Recent Findings and Perspectives.International journal of molecular sciences · 2024
    Review
  9. Article
  10. Review
  11. Article
  12. Interactions between gut microbes and NLRP3 inflammasome in the gut-brain axis.Computational and structural biotechnology journal · 2023
    Review
  13. Review
  14. Article
  15. Review
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Subrata SabuiDepartment of Physiology and Biophysics, School of Medicine, University of California, Irvine, California.
Jonathan SkupskyDepartment of Medicine, School of Medicine, University of California, Irvine, California.
Rubina KapadiaDepartment of Medicine, School of Medicine, University of California, Irvine, California.
Kyle CogburnDepartment of Physiology and Biophysics, School of Medicine, University of California, Irvine, California.
Nils W LambrechtDepartment of Medical Research, Veterans Affairs Medical Center, Long Beach, California.
Anshu AgrawalDepartment of Medicine, School of Medicine, University of California, Irvine, California.ORCID 0000-0002-3323-9152
Hamid M SaidDepartment of Physiology and Biophysics, School of Medicine, University of California, Irvine, California.
University of California, Irvine · USLong Beach Medical Center · US

Funding

INTESTINAL VITAMIN H UPTAKE--MOLECULAR/CELL REGULATIONR01DK058057 · NIDDK · UNIVERSITY OF CALIFORNIA-IRVINE · PI SAID, HAMID M · 2000 to 2019
$6.8M
Physiology/Pathophysiology of Vitamin B1 Transport in Pancreatic Acinar CellsR01AA018071 · NIAAA · UNIVERSITY OF CALIFORNIA-IRVINE · PI SAID, HAMID M · 2009 to 2023
$6.3M
Vitamin B1 (thiamin) transport in Alzheimer’s Disease: Role of microRNAs in regulating level of expression of its transporters (SLC19A2 & SLC19A3) in human brain cells and effect of hypoxiaR01DK056061 · NIDDK · UNIVERSITY OF CALIFORNIA-IRVINE · PI SAID, HAMID M · 1999 to 2024
$5.0M
NRSA Training CoreTL1TR001415 · NCATS · UNIVERSITY OF CALIFORNIA-IRVINE · PI CAIOZZO, VINCENT JAMES, HEAD, ELIZABETH · 2015 to 2023
$4.2M
Mechanism/Regulation of Intestinal Thiamin UptakeR37DK056061 · NIDDK · UNIVERSITY OF CALIFORNIA-IRVINE · PI SAID, HAMID M · 2009 to 2018
$3.6M
Impaired ability of aged human dendritic cells to maintain mucosal toleranceR01AG045216 · NIA · UNIVERSITY OF CALIFORNIA-IRVINE · PI AGRAWAL, ANSHU · 2014 to 2018
$1.6M
Functional Immunoimaging in the GI TractIK2BX003518 · VA · VETERANS HEALTH ADMINISTRATION · PI SKUPSKY, JONATHAN · 2018 to 2022
–
BLRD VA I01 BX001142BLRD VA IK2 BX003518NCATS NIH HHS TL1 TR001415NIAAA NIH HHS R01 AA018071NIA NIH HHS R01 AG045216NIDDK NIH HHS R01 DK056061NIDDK NIH HHS R01 DK058057NIDDK NIH HHS R37 DK056061
6 · The paper itself

Abstract

The sodium-dependent multivitamin transporter (SMVT;

Indexed as

AgingAnimalsBiotinBody WeightColonCytokinesDiarrheaEnteritisEstrogen AntagonistsGastrointestinal MicrobiomeIntestinesMiceMice, Inbred C57BLNF-kappa BNLR Family, Pyrin Domain-Containing 3 ProteinSignal TransductionBiotinbiotin transporterCytokinesEstrogen AntagonistsNF-kappa BNLR Family, Pyrin Domain-Containing 3 ProteinNlrp3 protein, mouseSymportersTamoxifenbiotininflammasomeintestinal inflammationmicrobiotaNF-κB activationSlc5a6SMVTtamoxifen-inducible knockout

Identifiers

PMID31369292
PMCPMC6842991
OpenAlexW2965123990

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.