Evidence map›Paper›PMID 31368892›Full record

ArticleeLife2019

Multivariate stochastic volatility modeling of neural data.

Tung D Phan, Jessica A Wachter, Ethan A Solomon, Michael J Kahana

Open access · goldAbstract read
In one paragraph

Article in eLife, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. EEG decoders track memory dynamics.Nature communications · 2024
    Article
  3. Hippocampal Theta and Episodic Memory.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023
    Article
  4. Article
  5. Does data cleaning improve brain state classification?Journal of neuroscience methods · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Tung D PhanUniversity of Pennsylvania, Philadelphia, United States.ORCID 0000-0001-5957-7566
Jessica A WachterUniversity of Pennsylvania, Philadelphia, United States.
Ethan A SolomonUniversity of Pennsylvania, Philadelphia, United States.ORCID 0000-0003-0541-7588
Michael J KahanaUniversity of Pennsylvania, Philadelphia, United States.
University of Pennsylvania · US

Funding

Defense Advanced Research Projects Agency N66001-14-2-4032
6 · The paper itself

Abstract

Because multivariate autoregressive models have failed to adequately account for the complexity of neural signals, researchers have predominantly relied on non-parametric methods when studying the relations between brain and behavior. Using medial temporal lobe (MTL) recordings from 96 neurosurgical patients, we show that time series models with volatility described by a multivariate stochastic latent-variable process and lagged interactions between signals in different brain regions provide new insights into the dynamics of brain function. The implied volatility inferred from our process positively correlates with high-frequency spectral activity, a signal that correlates with neuronal activity. We show that volatility features derived from our model can reliably decode memory states, and that this classifier performs as well as those using spectral features. Using the directional connections between brain regions during complex cognitive process provided by the model, we uncovered perirhinal-hippocampal desynchronization in the MTL regions that is associated with successful memory encoding.

Indexed as

Mental RecallModels, NeurologicalBiostatisticsElectroencephalographyHumansTemporal Lobecomputational biologyfree-recallhumaniEEGmachine learningmodel-based connectivityneurosciencestochastic volatilitysystems biology

Identifiers

PMID31368892
PMCPMC6697415
OpenAlexW2964851717

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.