ArticleeLife2019
Mapping the human subcortical auditory system using histology, postmortem MRI and in vivo MRI at 7T.
Article in eLife, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers.
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Who cites it
51 citing papers in PubMed, 90 citations in OpenAlex.
- Structural connectivity of auditory-linguistic brain networks predicts success in speech categorization and listening in noise.Neuroscience · 2026Article
- Neurophysiological Evidence for Reduced Use of Prior Sound Patterns to Shape Speech Processing in Autism.bioRxiv : the preprint server for biology · 2026Article
- Multiscale characterization of the human claustrum from histology to MRI.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Evaluating Approaches for Inference Testing of Whole-Brain Densely Sampled Single-Subject Task fMRI Data.bioRxiv : the preprint server for biology · 2026Article
- Mapping whole-brain auditory activation with 3T multi-echo fMRI at the group and individual-subject level.Hearing research · 2026Article
- A unified 3D reconstruction of microscopy and MRI in a brain showing Alzheimer's disease-related neuropathology.Brain pathology (Zurich, Switzerland) · 2026Article
- Parallel encoding of speech in human frontal and temporal lobes.Nature communications · 2025Article
- Mapping Whole-Brain Auditory Activation with 3T Multi-Echo fMRI at the Group and Individual-Subject Level.bioRxiv : the preprint server for biology · 2025Article
- Increased basal ganglia volume in older adults with tinnitus.Scientific reports · 2025Article
- Multiscale gradients of corticopontine structural connectivity.Scientific reports · 2025Article
- Reorganization of central auditory pathways in vestibular schwannoma: a diffusion tensor imaging study.Neuroradiology · 2025Observational
- A roadmap towards standardized neuroimaging approaches for human thalamic nuclei.Nature reviews. Neuroscience · 2024Review
- Individual Differences in the Impact of Distracting Environmental Sounds on the Performance of a Continuous Visual Task in Older Adults.Brain sciences · 2024Article
- Abnormal structural‒functional coupling patterning in progressive supranuclear palsy is associated with diverse gradients and histological features.Communications biology · 2024Article
- Segmentation of supragranular and infragranular layers in ultra-high-resolution 7T ex vivo MRI of the human cerebral cortex.Cerebral cortex (New York, N.Y. : 1991) · 2024Article
- Cortical-subcortical interactions underlie processing of auditory predictions measured with 7T fMRI.Cerebral cortex (New York, N.Y. : 1991) · 2024Article
- Dual Representation of the Auditory Space.Brain sciences · 2024Review
- Role of autonomic, nociceptive, and limbic brainstem nuclei in core autism features.Autism research : official journal of the International Society for Autism Research · 2024Article
- Multiple Concurrent Predictions Inform Prediction Error in the Human Auditory Pathway.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
- Functional localization of the human auditory and visual thalamus using a thalamic localizer functional magnetic resonance imaging task.Imaging neuroscience (Cambridge, Mass.) · 2024Article
Corrections and comments
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Authors and funding
8 authors at 4 institutions in 2 countries.
Funding
Abstract
Studying the human subcortical auditory system non-invasively is challenging due to its small, densely packed structures deep within the brain. Additionally, the elaborate three-dimensional (3-D) structure of the system can be difficult to understand based on currently available 2-D schematics and animal models. Wfe addressed these issues using a combination of histological data, post mortem magnetic resonance imaging (MRI), and in vivo MRI at 7 Tesla. We created anatomical atlases based on state-of-the-art human histology (BigBrain) and postmortem MRI (50 µm). We measured functional MRI (fMRI) responses to natural sounds and demonstrate that the functional localization of subcortical structures is reliable within individual participants who were scanned in two different experiments. Further, a group functional atlas derived from the functional data locates these structures with a median distance below 2 mm. Using diffusion MRI tractography, we revealed structural connectivity maps of the human subcortical auditory pathway both in vivo (1050 µm isotropic resolution) and post mortem (200 µm isotropic resolution). This work captures current MRI capabilities for investigating the human subcortical auditory system, describes challenges that remain, and contributes novel, openly available data, atlases, and tools for researching the human auditory system.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.