ArticlePlant biotechnology journal2020
De novo assembly of a wild pear (Pyrus betuleafolia) genome.
Article in Plant biotechnology journal, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 73 papers.
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73 citing papers in PubMed, 133 citations in OpenAlex.
- A high-quality haplotype-resolved genome of Pyrus calleryana provides insights into adaptive gene families.The plant genome · 2026Article
- 3D Chromatin Architecture Provides Insights Into Leaf Trait Variation Among Pear Species.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Pan-Genome and Transcriptome-Guided Analysis Reveals Duplication-Driven Evolution and Candidate MYB-bHLH Modules Associated with Fruit Development in Pear.Plants (Basel, Switzerland) · 2026Article
- Whole-genome resequencing of 495Horticulture research · 2026Article
- Pangenome-wide identification of chloroplast RNA splicing and ribosome maturation (CRM) genes in eight Pyrus genomes indicated their involvement in multiple stresses.Scientific reports · 2026Article
- Genome-Wide Characterization of thePlants (Basel, Switzerland) · 2026Article
- Haplotype-resolved chromosome-level genome assemblies of nineteen apple (Malus domestica Borkh.) cultivars.Scientific data · 2026Article
- Development and application of a multiple nucleotide polymorphism (MNP)-based molecular identification system for pear cultivars.BMC plant biology · 2025Article
- Convergent domestication of bitter apples and pears by selecting mutations of MYB transcription factors to reduce proanthocyanidin levels.Molecular horticulture · 2025Article
- Pear scab resistance gene Rvn1 from Ussurian pear is located in a cluster of receptor-like protein ethylene-inducing Xylanase (EIX) genes.BMC plant biology · 2025Article
- Comparative genomic analyses reveal different genetic basis of two types of fruit in Maloideae.Nature communications · 2025Article
- Haplotype-resolved T2T genome assembly of the pear cultivar 'Danxiahong'.Scientific data · 2025Article
- Article
- A chromosome-scale and haplotype-resolved genome assembly of tetraploid blackberry (Horticulture research · 2025Article
- Gap-free genome assemblies of two Pyrus bretschneideri cultivars and GWAS analyses identify a CCCH zinc finger protein as a key regulator of stone cell formation in pear fruit.Plant communications · 2025Article
- Long-read genome sequencing reveals the sequence characteristics of pear self-incompatibility locus.Molecular horticulture · 2025Article
- Telomere-to-telomere Genome Assembly of two representative Asian and European pear cultivars.Scientific data · 2024Article
- Transcription Factors Are Involved in Wizened Bud Occurrence During the Growing Season in theEpigenomes · 2024Article
- Haplotype-resolved T2T genome assemblies and pangenome graph of pear reveal diverse patterns of allele-specific expression and the genomic basis of fruit quality traits.Plant communications · 2024Article
- A Haplotype-resolved, Chromosome-scale Genome for Malus domestica Borkh. 'WA 38'.G3 (Bethesda, Md.) · 2024Article
13 more citing papers are in PubMed but not listed here.
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15 authors at 3 institutions in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
China is the origin and evolutionary centre of Oriental pears. Pyrus betuleafolia is a wild species native to China and distributed in the northern region, and it is widely used as rootstock. Here, we report the de novo assembly of the genome of P. betuleafolia-Shanxi Duli using an integrated strategy that combines PacBio sequencing, BioNano mapping and chromosome conformation capture (Hi-C) sequencing. The genome assembly size was 532.7 Mb, with a contig N50 of 1.57 Mb. A total of 59 552 protein-coding genes and 247.4 Mb of repetitive sequences were annotated for this genome. The expansion genes in P. betuleafolia were significantly enriched in secondary metabolism, which may account for the organism's considerable environmental adaptability. An alignment analysis of orthologous genes showed that fruit size, sugar metabolism and transport, and photosynthetic efficiency were positively selected in Oriental pear during domestication. A total of 573 nucleotide-binding site (NBS)-type resistance gene analogues (RGAs) were identified in the P. betuleafolia genome, 150 of which are TIR-NBS-LRR (TNL)-type genes, which represented the greatest number of TNL-type genes among the published Rosaceae genomes and explained the strong disease resistance of this wild species. The study of flavour metabolism-related genes showed that the anthocyanidin reductase (ANR) metabolic pathway affected the astringency of pear fruit and that sorbitol transporter (SOT) transmembrane transport may be the main factor affecting the accumulation of soluble organic matter. This high-quality P. betuleafolia genome provides a valuable resource for the utilization of wild pear in fundamental pear studies and breeding.
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