Evidence map›Paper›PMID 31368477›Full record

ArticleBioinformatics (Oxford, England)2019

PyMethylProcess-convenient high-throughput preprocessing workflow for DNA methylation data.

Joshua J Levy, Alexander J Titus, Lucas A Salas, Brock C Christensen

Abstract read
In one paragraph

Article in Bioinformatics (Oxford, England), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Joshua J LevyDepartment of Epidemiology, Geisel School of Medicine at Dartmouth.
Alexander J TitusDepartment of Epidemiology, Geisel School of Medicine at Dartmouth.
Lucas A SalasDepartment of Epidemiology, Geisel School of Medicine at Dartmouth.
Brock C ChristensenDepartment of Epidemiology, Geisel School of Medicine at Dartmouth.

Funding

Relation Between In-utero Vitamin D and Immune Function in Early Childhood P20GM104416 · NIGMS · DARTMOUTH COLLEGE · PI CHRISTENSEN, BROCK CLARKE · 2013 to 2022
$23.7M
(PQ3) Immune epigenetic biomarkers of bladder cancer outcomesR01CA216265 · NCI · DARTMOUTH COLLEGE · PI CHRISTENSEN, BROCK CLARKE · 2017 to 2021
$2.9M
MicroRNA related genetic variation and head and neck cancerR01DE022772 · NIDCR · DARTMOUTH COLLEGE · PI CHRISTENSEN, BROCK CLARKE · 2013 to 2016
$2.7M
NCI NIH HHS R01 CA216265NIDCR NIH HHS R01 DE022772NIGMS NIH HHS P20 GM104416
6 · The paper itself

Abstract

summaryPerforming highly parallelized preprocessing of methylation array data using Python can accelerate data preparation for downstream methylation analyses, including large scale production-ready machine learning pipelines. We present a highly reproducible, scalable pipeline (PyMethylProcess) that can be quickly set-up and deployed through Docker and PIP. AVAILABILITY AND IMPLEMENTATION: Project Home Page: https://github.com/Christensen-Lab-Dartmouth/PyMethylProcess. Available on PyPI (pymethylprocess), Docker (joshualevy44/pymethylprocess). SUPPLEMENTARY INFORMATION: Supplementary data are available at Bioinformatics online.

Indexed as

DNA MethylationWorkflowComputational BiologyMachine LearningSoftware

Identifiers

PMID31368477
PMCPMC6954637

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.