Evidence map›Paper›PMID 31368326›Full record

ArticleThe Onderstepoort journal of veterinary research2019

Acaricidal activity of the aqueous and hydroethanolic extracts of 15 South African plants against Rhipicephalus turanicus and their toxicity on human liver and kidney cells.

Gerda Fouche, Olubukola T Adenubi, Tlabo Leboho, Lyndy J McGaw, Vinny Naidoo, Kevin W Wellington, Jacobus N Eloff

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in The Onderstepoort journal of veterinary research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 19 citations in OpenAlex.

  1. Phytochemical Screening and in-vitro Efficacy ofJournal of experimental pharmacology · 2024
    Article
  2. Article
  3. Article
  4. Article
  5. Effect of polyphenols extracted fromJournal of parasitic diseases : official organ of the Indian Society for Parasitology · 2021
    Article
  6. Review
  7. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Gerda FoucheChemistry Department, Faculty of Natural and Agricultural Sciences, University of Pretoria, Pretoria. foucheg51@gmail.com.
Olubukola T Adenubi
Tlabo Leboho
Lyndy J McGaw
Vinny Naidoo
Kevin W Wellington
Jacobus N Eloff
University of Pretoria · ZAOnderstepoort Veterinary Academic Hospital · ZA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hot water and hydroethanolic (70:30) extracts were prepared from 15 plant species, which were investigated to discover eco-friendly and less expensive tick control methods as an alternative to synthetic acaricides. A contact bioassay was used to determine the acaricidal activity of these extracts against the cattle tick, Rhipicephalus turanicus (Acari: Ixodidae) at a concentration of 20% (200 mg/mL). The hydroethanolic extracts had better activity than the hot water extracts against R. turanicus. The hydroethanolic extract from Tabernaemontana elegans (leaves) had the best mortality (87.0%). This was followed by Calpurnia aurea (stems) with a mortality of 75.0%, Schkuhria pinnata (whole plant) with a mortality of 67.0% and Aloe rupestris (leaves) with a mortality of 66.6%. The toxicity of the plant extracts was also investigated and it was found that most of the hydroethanolic and hot water extracts were either safe or very safe on human Vero kidney and liver HepG2 cells. From this study, it was evident that botanicals have the potential to be developed as environmentally benign natural acaricides against R. turanicus.

Indexed as

AcaricidesAnimalsChlorocebus aethiopsFemaleHep G2 CellsHumansKidneyLiverMagnoliopsidaMalePlant ExtractsRhipicephalusSpecies SpecificityAcaricidesPlant Extractsacaricidal activitycontact bioassayethanolHepG2 cellsRhipicephalus turanicustoxicityVero cellswater

Identifiers

PMID31368326
PMCPMC6676935
OpenAlexW2963033679

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.