ArticleClinical research in cardiology : official journal of the German Cardiac Society2020
Passive leg-lifting in heart failure patients predicts exercise-induced rise in left ventricular filling pressures.
Article in Clinical research in cardiology : official journal of the German Cardiac Society, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed.
- Utility of Simultaneous Left Atrial Strain-Volume Relationship During Passive Leg Lift to Identify Elevated Left Ventricular Filling Pressure-A Proof-of-Concept Study.Journal of clinical medicine · 2024Article
- Echocardiography in the Assessment of Heart Failure Patients.Diagnostics (Basel, Switzerland) · 2024Review
- Stress Echocardiography for Assessment of Diastolic Function.Current cardiology reports · 2024Review
- Pulmonary hypertension associated with left heart disease.The European respiratory journal · 2024Review
- Role of Echocardiography in Diabetic Cardiomyopathy: From Mechanisms to Clinical Practice.Journal of cardiovascular development and disease · 2023Review
- Noninvasive Point of Care Device for Assessing Cardiac Response to Acute Volume Changes.Medical devices (Auckland, N.Z.) · 2023Article
- The Role of Novel Cardiac Imaging for Contemporary Management of Heart Failure.Journal of clinical medicine · 2022Review
- The Value of Passive Leg Raise During Right Heart Catheterization in Diagnosing Heart Failure With Preserved Ejection Fraction.Circulation. Heart failure · 2022Article
- Passive Leg Raise: A Leg Up in the Diagnosis of Heart Failure With Preserved Ejection Fraction?Circulation. Heart failure · 2022Article
- Influence of Upright Versus Supine Position on Resting and Exercise Hemodynamics in Patients Assessed for Pulmonary Hypertension.Journal of the American Heart Association · 2022Article
- High prevalence of occult left ventricular diastolic dysfunction detected by exercise stress test in systemic sclerosis.Scientific reports · 2022Article
- Easy-to-use preload stress echocardiography by using combined dynamic postural stress can identify high-risk patients with heart failure with reduced ejection fraction.ESC heart failure · 2021Article
- Optimizing diastolic pressure gradient assessment.Clinical research in cardiology : official journal of the German Cardiac Society · 2020Article
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Authors and funding
6 authors.
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No grant is acknowledged in the PubMed record.
Abstract
aimThe aim of this study was to assess PCWP with passive leg-lifting (PLL) and exercise, in two groups of patients presenting with normal left ventricular ejection fraction (LVEF); one group with elevated NT-proBNP (eBNP), and one with normal NT-proBNP (nBNP) plasma concentration. METHODS AND
resultsFifty-one patients with eBNP (NT-proBNP ≥ 125 ng/l) and LVEF > 50%, were investigated and compared with 34 patients with nBNP (NT-proBNP < 125 ng/l) and LVEF > 50%. Both groups underwent right heart catheterization (RHC) at rest, PLL and exercise. From RHC, mean pulmonary arterial pressure (mPAP), cardiac output (CO), and PCWP were measured. All nBNP patients had PCWP < 15 mmHg at rest, and a PCWP of < 25 mmHg with PLL and during exercise. Patients with eBNP had higher (p < 0.01) resting mPAP, PCWP, and mPAP/CO. These values increased with exercise; however, CO increased less in comparison with nBNP patients (p = 0.001). 20% of patients with eBNP had a PCWP > 15 mmHg at rest, this percentage increased to 47% with PLL and 41% had a PCWP > 25 mmHg during exercise. Of those with PCWP > 25 mmHg during exercise, 91% had a PCWP > 15 mmHg with PLL. A PCWP > 15 mmHg on PLL had a 91% sensitivity and 92% specificity in predicting exercise-induced PCWP of > 25 mmHg.
conclusionIn patients presenting with eBNP, PLL can predict which patients will develop elevated PCWP with exercise. These findings highlight the role of stress assessment.
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