ArticleJournal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract2020
The Impact of Delays to Definitive Surgical Care on Survival in Colorectal Cancer Patients.
Article in Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 5 of them syntheses that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
15 citing papers in PubMed, 5 syntheses or guidelines pooled it.
- Pooled it
- Treatment delay significantly increases mortality in colorectal cancer: a meta-analysis.GeroScience · 2025Pooled it
- The effect of time before diagnosis and treatment on colorectal cancer outcomes: systematic review and dose-response meta-analysis.British journal of cancer · 2023Pooled it
- Delay to elective colorectal cancer surgery and implications for survival: a systematic review and meta-analysis.Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland · 2021Pooled it
- Gastrointestinal Malignancies and the COVID-19 Pandemic: Evidence-Based Triage to Surgery.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2020Pooled it
- Timeliness of Colorectal Cancer Care in Veterans: The Role of Travel Distance.Cancer reports (Hoboken, N.J.) · 2026Article
- The environmental impacts of surgical care pathways: same-day-discharge versus enhanced recovery following minimally invasive colectomy and stoma reversal.Surgical endoscopy · 2026Article
- Article
- Does waiting for surgery matter? How time from diagnostic MRI to resection affects outcomes in newly diagnosed glioblastoma.Journal of neurosurgery · 2024Article
- Three-Year Analysis of the Rectal Cancer Care Trajectory after the COVID-19 Pandemic.Diseases (Basel, Switzerland) · 2023Article
- Article
- The Challenges of Colorectal Cancer Surgery during the COVID-19 Pandemic in Romania: A Three-Year Retrospective Study.International journal of environmental research and public health · 2022Article
- Interhospital referral of colorectal cancer patients: a Dutch population-based study.International journal of colorectal disease · 2021Article
- Applying Latent Class Analysis on Cancer Registry Data to Identify and Compare Health Disparity Profiles in Colorectal Cancer Surgical Treatment Delay.Journal of public health management and practice : JPHMPArticle
- Preoperative optimization: Physical and cognitive pre-habilitation and management of chronic medication.Saudi journal of anaesthesiaReview
Corrections and comments
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Authors and funding
12 authors.
Funding
Abstract
introductionTreatment delay may have detrimental effects on cancer outcomes. The impact of longer delays on colorectal cancer outcomes remains poorly described. The objective of this study was to determine the effect of delays to curative-intent surgical resection on survival in colorectal cancer patients.
methodsAll adult patients undergoing elective resection of primary non-metastatic colorectal adenocarcinoma from January 2009 to December 2014 were reviewed. Treatment delays were defined as the time from tissue diagnosis to definitive surgery, categorized as < 4, 4 to < 8, and ≥ 8 weeks. Primary outcomes were 5-year disease-free (DFS) and overall survival (OS). Statistical analysis included Kaplan-Meier curves and Cox regression models.
resultsA total of 408 patients were included (83.2% colon;15.8% rectal) with a mean follow-up of 58.4 months (SD29.9). Fourteen percent (14.0%) of patients underwent resection < 4 weeks, 40.0% 4 to < 8 weeks, and 46.1% ≥ 8 weeks. More rectal cancer patients had treatment delay ≥ 8 weeks compared with colonic tumors (69.8% vs. 41.4%, p < 0.001). Cumulative 5-year DFS and OS were similar between groups (p = 0.558; p = 0.572). After adjusting for confounders, surgical delays were not independently associated with DFS and OS.
conclusionsTreatment delays > 4 weeks were not associated with worse oncologic outcomes. Delaying surgery to optimize patients can safely be considered without compromising survival.
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