Evidence map›Paper›PMID 31367850›Full record

ArticlePsychopharmacology2019

Impacts of inter-trial interval duration on a computational model of sign-tracking vs. goal-tracking behaviour.

François Cinotti, Alain R Marchand, Matthew R Roesch, Benoît Girard, Mehdi Khamassi

Open access · hybridAbstract readComparative Study
In one paragraph

Article in Psychopharmacology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 10 citations in OpenAlex.

  1. The spatiotemporal dynamics of conditioned behavior: First-order and higher-order conditioning.Journal of experimental psychology. Animal learning and cognition · 2025
    Article
  2. Review
  3. Reward-Mediated, Model-Free Reinforcement-Learning Mechanisms in Pavlovian and Instrumental Tasks Are Related.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

François CinottiCNRS, Institut des Systèmes Intelligents et de Robotique (ISIR), Équipe AMAC, Sorbonne Université, 4 Place Jussieu, 75252, Paris cedex 05, France. francois.cinotti@isir.upmc.fr.ORCID http://orcid.org/0000-0003-2921-0901
Alain R MarchandCNRS, Institut de Neurosciences Cognitives et Intégratives d'Aquitaine (INCIA, UMR5287), Bordeaux, France.
Matthew R RoeschDepartment of Psychology, University of Maryland, College Park, MD, USA.
Benoît GirardCNRS, Institut des Systèmes Intelligents et de Robotique (ISIR), Équipe AMAC, Sorbonne Université, 4 Place Jussieu, 75252, Paris cedex 05, France.
Mehdi KhamassiCNRS, Institut des Systèmes Intelligents et de Robotique (ISIR), Équipe AMAC, Sorbonne Université, 4 Place Jussieu, 75252, Paris cedex 05, France.
Centre National de la Recherche Scientifique · FRUniversity of Maryland, College Park · US

Funding

CRCNS:US-Fr Research: Neurobehavioral Assessment of a Reward Learning ModelR01DA040993 · NIDA · UNIV OF MARYLAND, COLLEGE PARK · PI ROESCH, MATTHEW R · 2015 to 2017
$402k
Agence Nationale de la Recherche ANR-15-NEUC-0001NIDA NIH HHS R01 DA040993
6 · The paper itself

Abstract

In the context of Pavlovian conditioning, two types of behaviour may emerge within the population (Flagel et al. Nature, 469(7328): 53-57, 2011). Animals may choose to engage either with the conditioned stimulus (CS), a behaviour known as sign-tracking (ST) which is sensitive to dopamine inhibition for its acquisition, or with the food cup in which the reward or unconditioned stimulus (US) will eventually be delivered, a behaviour known as goal-tracking (GT) which is dependent on dopamine for its expression only. Previous work by Lesaint et al. (PLoS Comput Biol, 10(2), 2014) offered a computational explanation for these phenomena and led to the prediction that varying the duration of the inter-trial interval (ITI) would change the relative ST-GT proportion in the population as well as phasic dopamine responses. A recent study verified this prediction, but also found a rich variance of ST and GT behaviours within the trial which goes beyond the original computational model. In this paper, we provide a computational perspective on these novel results.

Indexed as

Computer SimulationGoalsAnimalsConditioning, ClassicalConditioning, OperantDopamineMaleMotivationRewardTime FactorsDopamineGoal-trackingReinforcement learningSign-tracking

Identifiers

PMID31367850
PMCPMC6695359
OpenAlexW2965838618

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.