Evidence map›Paper›PMID 31367837›Full record

ArticleEJNMMI research2019

Human biodistribution and radiation dosimetry of the 5-HT

Annette Johansen, Søren Holm, Bente Dall, Sune Keller, Jesper L Kristensen, Gitte M Knudsen, Hanne D Hansen

Open access · goldAbstract read
In one paragraph

Article in EJNMMI research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Article
  3. Radiotracers for the Central Serotoninergic System.Pharmaceuticals (Basel, Switzerland) · 2022
    Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Annette JohansenNeurobiology Research Unit and Center for Integrated Molecular Brain Imaging, Rigshospitalet, Building 6931, Blegdamsvej 9, DK-2100, Copenhagen, Denmark.
Søren HolmPET and Cyclotron Unit, Rigshospitalet, Copenhagen, Denmark.
Bente DallPET and Cyclotron Unit, Rigshospitalet, Copenhagen, Denmark.
Sune KellerPET and Cyclotron Unit, Rigshospitalet, Copenhagen, Denmark.
Jesper L KristensenDepartment of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Gitte M KnudsenNeurobiology Research Unit and Center for Integrated Molecular Brain Imaging, Rigshospitalet, Building 6931, Blegdamsvej 9, DK-2100, Copenhagen, Denmark. gmk@nru.dk.ORCID http://orcid.org/0000-0003-1508-6866
Hanne D HansenNeurobiology Research Unit and Center for Integrated Molecular Brain Imaging, Rigshospitalet, Building 6931, Blegdamsvej 9, DK-2100, Copenhagen, Denmark.
Rigshospitalet · DKUniversity of Copenhagen · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCimbi-36 can be

resultsThe effective dose was only slightly higher for

conclusionThe low effective dose of 5.5 μSv/MBq allows for the injection of up to 1.8 GBq for healthy volunteers per study (equivalent to 3 scans if injecting 600 MBq) and still stay below the international guidelines of 10 mSv, making

Indexed as

11C-Cimbi-3625B-NBOMe5-HT2A receptorBiodistributionPharmacokineticsPharmacologyPositron emission tomographyRadiation dosimetry

Identifiers

PMID31367837
PMCPMC6669221
OpenAlexW2965802642

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.