ArticleEJNMMI research2019
Optimization of parathyroid
Article in EJNMMI research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 27 citations in OpenAlex.
- Molecular Imaging in Parathyroid Carcinoma Management: A Comprehensive Review.Life (Basel, Switzerland) · 2025Review
- Dynamic, multiphase magnetic resonance imaging of in vivo physiological processes with long-lived hyperpolarizedScience advances · 2025Article
- Up-to-Date Imaging for Parathyroid Tumor Localization in MEN1 Patients with Primary Hyperparathyroidism: When and Which Ones (A Narrative Pictorial Review).Diagnostics (Basel, Switzerland) · 2024Review
- Pancreatitis with Intraabdominal Venous Thrombosis as an Initial Presentation of Parathyroid Adenoma: A Rare Clinical Presentation.The American journal of case reports · 2024Article
- Head-to-head comparison of [European journal of nuclear medicine and molecular imaging · 2024Article
- The EANM practice guidelines for parathyroid imaging.European journal of nuclear medicine and molecular imaging · 2021Article
- Locating hyperfunctioning parathyroid glands usingEuropean journal of hybrid imaging · 2021Article
- Review
- Article
- A retrospective analysis of the diagnostic performance ofEJNMMI research · 2021Article
- Diagnostic Value of Choline PET in the Preoperative Localization of Hyperfunctioning Parathyroid Gland(s): A Comprehensive Overview.Biomedicines · 2021Review
- WillEndocrine · 2021Review
- Article
Corrections and comments
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Authors and funding
13 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo evaluate the optimal tracer uptake time, the minimal amount of radioactivity and the inter-observer agreement for
methodsTwenty-one patients with biochemically proven pHPT were retrospectively studied after injection of 6.3 ± 1.2 MBq/kg
resultsSUVpeak of the adenoma decreased from 30 to 40 p.i. onwards. All adenoma/background contrast ratios did not differ from 20- to 30-min p.i. onwards. The SUVs of adenoma in the scan duration of 1, 2.5, and 5 min all differed significantly from the same SUV in the 10-min scan duration (all p = 0.012). However, the difference in absolute SUV adenoma values was well below 10% and therefore not considered clinically significant. The inter-observer analysis showed that the Fleiss' kappa of the 1-min scan were classified as "moderate," while these values were classified as "good" in the 2.5-, 5-, and 10-min scan duration. Observers scored lower certainty scores in the 1- and 2.5-min scans compared to the 5- and 10-min scan durations.
conclusionThe optimal time to start PET/CT scanning in patients with pHPT is 20 min after mean injection of 6.3 MBq/kg
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