Evidence map›Paper›PMID 31367701›Full record

ArticleChronic diseases and translational medicine2019

Association of hemoglobin with arterial stiffness evaluated by carotid-femoral pulse wave velocity among Chinese adults.

Zhen-Zhen Zhang, Ping Wang, Xiang-Lei Kong, Wen-Li Mao, Mei-Yu Cui

Abstract read
In one paragraph

Article in Chronic diseases and translational medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Attenuated cardiac autonomic function in humans with high-affinity hemoglobin and compensatory polycythemia.American journal of physiology. Regulatory, integrative and comparative physiology · 2023
    Article
  4. Article
  5. Telomere shortening in patients on long-term hemodialysis.Chronic diseases and translational medicine · 2021
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Zhen-Zhen ZhangTaishan Medical University, Tai'an, Shandong 271000, China.
Ping WangDepartment of Nephrology, Qianfoshan Hospital Affiliated to Shandong University, Jinan, Shandong 250014, China.
Xiang-Lei KongDepartment of Nephrology, Qianfoshan Hospital Affiliated to Shandong University, Jinan, Shandong 250014, China.
Wen-Li MaoTaishan Medical University, Tai'an, Shandong 271000, China.
Mei-Yu CuiDepartment of Nephrology, Qianfoshan Hospital Affiliated to Shandong University, Jinan, Shandong 250014, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveIncreased hemoglobin (Hb) levels are known to be associated with increased cardiovascular events and mortalities. Therefore, we assumed that high Hb levels were associated with arterial stiffness. Pulse wave velocity (PWV) is a simple and noninvasive method for measuring arterial stiffness to assess cardiovascular disease in general populations. Accordingly, we conducted a cross-sectional study to explore the association of Hb with PWV.

methodsA total of 6642 adults aged 54.5 ± 11.2 years undergoing physical examinations were enrolled, 71.7% of whom were males. Arterial stiffness was evaluated by carotid-femoral PWV (cfPWV). Multivariable regression analyses were performed to determine the relationship between Hb and increased cfPWV.

resultsIn this study, the mean Hb (per 10 g/L increase) was 144.7 ± 13.9 g/L, and the mean cfPWV was 15.1 ± 3.1 m/s. cfPWV was significantly higher in high hemoglobin groups ≥15.4 g/L (Quartile 4) than in the lowest hemoglobin group (Quartile 1 ≤ 13.6 g/L;

conclusionThis study demonstrated that Hb levels significantly correlate with increased cfPWV.

Indexed as

Arterial stiffnessCardiovascular diseasesHemoglobinPulse wave velocity

Identifiers

PMID31367701
PMCPMC6656875

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.