ArticleWorld journal of clinical cases2019
Chronic progression of recurrent orthokeratinized odontogenic cyst into squamous cell carcinoma: A case report.
Article in World journal of clinical cases, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
6 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.
- Primary intraosseous squamous cell carcinoma arising from an odontogenic keratocyst: case series and literature review.Medicina oral, patologia oral y cirugia bucal · 2021Pooled it
- Orthokeratinized Odontogenic Cyst in the Posterior Maxilla and Its Surgical Management: A Report of a Rare Case.Cureus · 2025Article
- Integrating single-cell sequencing and clinical insights to explore malignant transformation in odontogenic keratocyst.Computational and structural biotechnology journal · 2025Article
- Orthokeratinised odontogenic cyst: A case series.Journal of oral and maxillofacial pathology : JOMFP · 2023Article
- Primary intraosseous carcinoma arising in orthokeratinized odontogenic cyst.Journal of dental sciences · 2020Article
- Incidental finding of orthokeratinized odontogenic cyst with unusual features.Journal of oral and maxillofacial pathology : JOMFPArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundOrthokeratinized odontogenic cyst (OOC) is a benign odontogenic cyst. It is a variant of the common odontogenic keratocyst (OKC). This case report describes a rare malignant transformation of OOC, with the aim of raising awareness of the malignant potential of OOC and distinguishing it from OKC. CASE SUMMARY: In August 2018, a 52-year-old man was referred to the Department of Oral Maxillofacial and Head-Neck Oncology of Wuhan University. The patient presented with severe pain in the left mandible for 2 mo, and had a 5-year history of osteomyelitis and mandibular cyst with three recurrences. His latest diagnosis by pathological examination was OOC of the left mandible with mild-to-moderate local proliferation. However, the cyst showed malignant potential by radiographic examination. We performed partial mandibulectomy and sent the lesion tissue for pathological examination. As expected, the cyst had deteriorated to moderately differentiated squamous cell carcinoma. During postoperative follow-up, the patient went for chemotherapy in September 2018 and successfully completed four cycles.
conclusionSurgeons should be more aware of OOC, which is usually benign but can become malignant.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.