Evidence map›Paper›PMID 31367598›Full record

ArticleSkin appendage disorders2019

Fibrosing Alopecia in a Pattern Distribution (FAPD) in 16 African-Descent and Hispanic Female Patients: A Challenging Diagnosis.

Marcelo de Souza Teixeira, Maria Fernanda Reis Gavazzoni Dias, Ralph M Trüeb, Mayra Carrijo Rochael, Enoi Aparecida Guedes Vilar

Open access · bronzeAbstract read
In one paragraph

Article in Skin appendage disorders, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
3.2field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 22 citations in OpenAlex.

  1. Scalp Biopsies for Alopecia.Dermatopathology (Basel, Switzerland) · 2026
    Review
  2. Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. Trichoscopy for the Hair Transplant Surgeon-Assessing for Mimickers of Androgenetic Alopecia and Preoperative Evaluation of Donor Site Area.Indian journal of plastic surgery : official publication of the Association of Plastic Surgeons of India · 2021
    Review
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Marcelo de Souza TeixeiraDepartment of Dermatology, Hospital Universitário Antonia Pedro, Universidade Federal Fluminense, Niterói, Brazil.
Maria Fernanda Reis Gavazzoni DiasDepartment of Dermatology, Hospital Universitário Antonia Pedro, Universidade Federal Fluminense, Niterói, Brazil.
Ralph M TrüebCenter for Dermatology and Hair Diseases Professor Trüeb, Wallisellen, Switzerland.
Mayra Carrijo RochaelDivision of Dermatopathology, Department of Dermatology, Universidade Federal Fluminense, Niterói, Brazil.
Enoi Aparecida Guedes VilarDivision of Dermatopathology, Department of Dermatology, Universidade Federal Fluminense, Niterói, Brazil.
Universidade Federal Fluminense · BRHospital Universitário Antônio Pedro · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundFibrosing alopecia in a pattern distribution (FAPD) has only been described in Caucasian patients, and it is not clear whether it can develop in dark-skin ethnicities. MATERIALS AND

methodsSixteen Brazilian female patients, 12 of African descent and 4 Hispanic, with progressive scarring alopecia in a pattern distribution were analyzed.

resultsDermatoscopic features showed perifollicular erythema and scaling (14/16), hair fiber diameter diversity (16/16), loss of follicular ostia (16/16), and follicular keratosis (3/16). Late stages showed a honeycomb pigmented network (12/16), a hyperpigmented perifollicular halo (12/16), and small white patches (12/16). Histopathological features showed lichenoid perifollicular infiltrate (14/16), follicular miniaturization (16/16), concentric fibrosis (16/16), perifollicular lymphocytic infiltrate (16/16), and vellus hair involvement (10/16). Premature desquamation of the inner root sheath was found in 11 patients.

conclusionsThe concomitant findings of cicatricial pattern hair loss (with or without the recess of the front hair line), hair fiber diversity, perifollicular erythema and scaling, a whitish perifollicular halo, and histological findings of androgenetic alopecia, with vacuolar interface alteration of the upper portion of the follicular epithelium, are the main key features to suggest the diagnosis of FAPD. FAPD is a possible diagnosis in patients of color with cicatricial pattern hair loss. Clinical, dermatoscopic, and histopathological examination allow a proper final differential diagnosis.

Indexed as

Androgenetic alopeciaCicatricial alopeciaFemale alopeciaFibrosing alopecia in a pattern distribution

Identifiers

PMID31367598
PMCPMC6615333
OpenAlexW2920227858

What OpenQuestion holds

Textmetadata
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.