Evidence map›Paper›PMID 31367591›Full record

ArticleOcular oncology and pathology2019

Monte Carlo Simulation of the Treatment of Uveal Melanoma Using Measured Heterogeneous

Francisco J Zaragoza, Marion Eichmann, Dirk Flühs, Andrea Wittig, Wolfgang Sauerwein, Lorenzo Brualla

Open access · bronzeAbstract read
In one paragraph

Article in Ocular oncology and pathology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Francisco J ZaragozaNCTeam, Strahlenklinik, Universitätsklinikum Essen, Essen, Germany.
Marion EichmannFakultät Physik, Technische Universität Dortmund, Dortmund, Germany.
Dirk FlühsNCTeam, Strahlenklinik, Universitätsklinikum Essen, Essen, Germany.
Andrea WittigKlinik für Strahlentherapie und Radioonkologie, Universitätsklinikum Jena, Jena, Germany.
Wolfgang SauerweinNCTeam, Strahlenklinik, Universitätsklinikum Essen, Essen, Germany.
Lorenzo BruallaWest German Proton Therapy Centre Essen (WPE), Essen, Germany.
Essen University Hospital · DEKlinik und Poliklinik für Strahlentherapie und Radioonkologie · DETU Dortmund University · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

aimsRuthenium plaques are used for the treatment of ocular tumors. The aim of this work is the comparison between simulated absorbed dose distributions tallied in an anthropomorphic phantom, obtained from ideal homogeneous plaques, and real eye plaques in which the actual heterogeneous distribution of

methodsThe generic CCA and CCB, and the specific CCA1364 and CCB1256

resultsEccentric placements of the plaques, taking into account the inhomogeneities of the emitter map, can substantially reduce the dose delivered to structures at risk while maintaining the prescribed dose at the tumor apex.

conclusionsThe emitter map distribution of the plaque and the computerized tomography of the patient used in a Monte Carlo simulation allow an accurate determination of the plaque position with respect to the tumor with the potential to reduce the dose to sensitive structures.

Indexed as

Beta emitterBrachytherapyEye plaquesMonte Carlo simulationPENELOPERutheniumTreatment planningUveal melanoma

Identifiers

PMID31367591
PMCPMC6615327
OpenAlexW2897404673

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.