Evidence map›Paper›PMID 31367508›Full record

ArticleChemistryOpen2019

Design and Synthesis of Imidazole and Triazole Pyrazoles as

Safaa M Kishk, Kirsty J McLean, Sakshi Sood, Darren Smith, Jack W D Evans, Mohamed A Helal, Mohamed S Gomaa, Ismail Salama, Samia M Mostafa, Luiz Pedro S de Carvalho and 3 more

Open access · goldAbstract read
In one paragraph

Article in ChemistryOpen, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 31 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Structure-Function Analysis of the EssentialInternational journal of molecular sciences · 2024
    Article
  6. Metabolic Rewiring ofMetabolites · 2024
    Review
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 3 countries.

Safaa M KishkSchool of Pharmacy & Pharmaceutical Sciences Cardiff University King Edward VII Avenue Cardiff CF10 3NB U.K.
Kirsty J McLeanManchester Institute of Biotechnology, School of Chemistry University of Manchester 131 Princess Street Manchester M1 7DN U.K.
Sakshi SoodMycobacterial Metabolism and Antibiotic Research Laboratory The Francis Crick Institute 1 Midland Road London NW1 1AT U.K.
Darren SmithSchool of Pharmacy & Pharmaceutical Sciences Cardiff University King Edward VII Avenue Cardiff CF10 3NB U.K.
Jack W D EvansSchool of Pharmacy & Pharmaceutical Sciences Cardiff University King Edward VII Avenue Cardiff CF10 3NB U.K.
Mohamed A HelalMedicinal Chemistry Department, Faculty of Pharmacy Suez Canal University Ismailia Egypt.
Mohamed S GomaaMedicinal Chemistry Department, Faculty of Pharmacy Suez Canal University Ismailia Egypt.
Ismail SalamaMedicinal Chemistry Department, Faculty of Pharmacy Suez Canal University Ismailia Egypt.
Samia M MostafaMedicinal Chemistry Department, Faculty of Pharmacy Suez Canal University Ismailia Egypt.
Luiz Pedro S de CarvalhoMycobacterial Metabolism and Antibiotic Research Laboratory The Francis Crick Institute 1 Midland Road London NW1 1AT U.K.
Colin W LevyManchester Institute of Biotechnology, School of Chemistry University of Manchester 131 Princess Street Manchester M1 7DN U.K.
Andrew W MunroManchester Institute of Biotechnology, School of Chemistry University of Manchester 131 Princess Street Manchester M1 7DN U.K.
Claire SimonsSchool of Pharmacy & Pharmaceutical Sciences Cardiff University King Edward VII Avenue Cardiff CF10 3NB U.K.ORCID 0000-0002-9487-1100
Suez Canal University · EGCardiff University · GBUniversity of Manchester · GBThe Francis Crick Institute · GB

Funding

Biotechnology and Biological Sciences Research Council BB/M017702/1Medical Research Council FC001060Wellcome Trust FC001060
6 · The paper itself

Abstract

The emergence of untreatable drug-resistant strains of

Indexed as

Binding affinityImidazole derivativesmolecular modellingmycobacterium tuberculosisX-ray crystallography

Identifiers

PMID31367508
PMCPMC6646865
OpenAlexW2975352659

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.