ReviewClinical diabetes and endocrinology2019
Interpretation of common endocrine laboratory tests: technical pitfalls, their mechanisms and practical considerations.
Review in Clinical diabetes and endocrinology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed.
- Interference by vitamin B12-macrocomplexes: towards an effective detection and correct interpretation of hypo- and hypervitaminemia.Advances in laboratory medicine · 2024Article
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- Diagnostic pitfalls in assessment of ferritin following CAR-T-cell therapy: Understanding the hook effect.Pediatric blood & cancer · 2024Article
- MacroTSH: still a big problem for clinicians and clinical biochemists: lessons from a case report.European thyroid journal · 2024Article
- Selective peripheral tissue response to high testosterone levels in an infertile woman without virilization signs.Endocrinology, diabetes & metabolism case reports · 2024Article
- False diagnosis of recurrent thyroid carcinoma: the importance of testing for heterophile antibodies.Archives of endocrinology and metabolism · 2024Article
- Glucocorticoid signature of preterm infants developing bronchopulmonary dysplasia.Pediatric research · 2023Article
- Approach to the Patient With Prolactinoma.The Journal of clinical endocrinology and metabolism · 2023Review
- Effectiveness of combined seeds (pumpkin, sunflower, sesame, flaxseed): As adjacent therapy to treat polycystic ovary syndrome in females.Food science & nutrition · 2023Article
- Insulin Immunoassay Interference Due to Human Antimouse Antibodies in a Patient With Ketotic Hypoglycemia.JCEM case reports · 2023Article
- Spurious Serum Hormone Immunoassay Results: Causes, Recognition, Management.TouchREVIEWS in endocrinology · 2022Review
- Reference intervals of the sex hormonal profile in healthy women: A retrospective single-center study in Peru.Heliyon · 2022Article
- Article
- Article
- Hormone Immunoassay Interference: A 2021 Update.Annals of laboratory medicine · 2022Review
- Study protocol to develop a core outcome set for thyroid dysfunction to bridge the unmet needs of patient-centred care.BMJ open · 2021Article
- One-step-immunoassay of procalcitonin enables rapid and accurate diagnosis of bacterial infection.RSC advances · 2021Article
- Hypeprolactinemia: still an insidious diagnosis.Endocrine · 2021Article
- Common Pitfalls in the Interpretation of Endocrine Tests.Frontiers in endocrinology · 2021Review
- False elevation of serum cortisol in chemiluminescence immunoassay by Siemens Advia Centaur XP system in 21-hydroxylase deficiency: an 'endocrine laboma'.BMJ case reports · 2020Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Pitfalls in hormonal assays are commonly seen in clinical practice and may lead to erroneous clinical impressions and treatments. In this article, we address common laboratory pitfalls encountered during evaluation of patients with real or presumed endocrine disorders including high dose hook effect and falsely normal prolactin in cases of macroprolactinomas, macroprolactinemia and falsely elevated prolactin, macrothyrotropinemia and falsely elevated TSH, heterophile antibodies leading to false elevation of hormonal concentration, biotin interference with different hormonal assays, cross-reactivity of steroid hormones immunoassays, and others. We describe the mechanisms of such laboratory pitfalls, review clinical scenarios in which they might occur, and discuss the ways to resolve such conundrums. The aim of this article is to present a learning material for the endocrine trainees and practitioners.
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