Evidence map›Paper›PMID 31367343›Full record

ArticleAntimicrobial resistance and infection control2019

Susceptibility of livestock-associated methicillin-resistant

Kathleen Dittmann, Thomas Schmidt, Gerald Müller, Christiane Cuny, Silva Holtfreter, Daniel Troitzsch, Peter Pfaff, Nils-Olaf Hübner

Erratum issuedOpen access · goldAbstract readComparative Study
In one paragraph

Article in Antimicrobial resistance and infection control, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 21 citations in OpenAlex.

  1. Review
  2. Increasing usage of chlorhexidine in health care settings: blessing or curse? A narrative review of the risk of chlorhexidine resistance and the implications for infection prevention and control.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2022
    Review
  3. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Kathleen Dittmann1Institute of Hygiene and Environmental Medicine, University Medicine of Greifswald, Walther-Rathenau-Str. 49a, 17489 Greifswald, Germany.ORCID 0000-0001-9596-1530
Thomas Schmidt1Institute of Hygiene and Environmental Medicine, University Medicine of Greifswald, Walther-Rathenau-Str. 49a, 17489 Greifswald, Germany.
Gerald Müller1Institute of Hygiene and Environmental Medicine, University Medicine of Greifswald, Walther-Rathenau-Str. 49a, 17489 Greifswald, Germany.
Christiane Cuny2Robert Koch Institute, Unit 13: Nosocomial Pathogens and Antibiotic Resistances, Burgstraße 37, 38855 Wernigerode, Germany.
Silva Holtfreter3Department of Immunology, University of Greifswald, Ferdinand-Sauerbruch-Str, 17475 Greifswald, Germany.
Daniel Troitzsch1Institute of Hygiene and Environmental Medicine, University Medicine of Greifswald, Walther-Rathenau-Str. 49a, 17489 Greifswald, Germany.
Peter PfaffBBraun AG, Carl-Braun-Straße 1, 34212 Melsungen, Germany.
Nils-Olaf Hübner1Institute of Hygiene and Environmental Medicine, University Medicine of Greifswald, Walther-Rathenau-Str. 49a, 17489 Greifswald, Germany.
Universitätsmedizin Greifswald · DEB. Braun (Germany) · DERobert Koch Institute · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Recent publications have raised concerns of reduced susceptibilities of clinical bacterial isolates towards biocides. This study presents a comparative investigation of the susceptibility of livestock-associated Methicillin-resistant Methods: In total, 28 (18 LA-, 5 HA- and 5 CA) genetically characterized MRSA strains representing a broad spectrum of hosts, clonal complexes and spa-types, as well as the reference methicillin-sensitive Results: Results from the MIC/MBC and quantitative suspension tests revealed differences between antiseptic substances but not between epidemiological groups of MRSA strains. OCT and PHMB were the most active substances with a minimal MIC of 1 mg/L, followed by CHX (2 mg/L), TCX (32 mg/L) and finally PVP-I (1024 mg/L). The MSSA reference strain showed a tendency to a higher susceptibility compared to the MRSA strains. Conclusions: This investigation of the susceptibility of a range of LA-, HA- and CA-MRSA strains using standardized conditions gave no indication that LA-MRSA strains are less susceptible to commonly used antiseptics compared to HA- and CA-MRSA strains.

Indexed as

AnimalsAnti-Infective Agents, LocalBiguanidesChlorhexidineCommunity-Acquired InfectionsCross InfectionHumansIminesLivestockMethicillin-Resistant Staphylococcus aureusMicrobial Sensitivity TestsMicrobial ViabilityPovidone-IodinePyridinesStaphylococcal InfectionsTriclosanAnti-Infective Agents, LocalBiguanidesChlorhexidinechlorhexidine gluconateIminesoctenidinepolihexanidePovidone-IodinePyridinesTriclosanAntisepsisDecolonizationMRSAResistance

Identifiers

PMID31367343
PMCPMC6647070
OpenAlexW4252097606

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.