Evidence map›Paper›PMID 31367237›Full record

ArticleDiabetology & metabolic syndrome2019

Association between serum visfatin levels and atherosclerotic plaque in patients with type 2 diabetes.

Long-Yi Zheng, Xia Xu, Ren-Hui Wan, Sheng Xia, Jin Lu, Qin Huang

Open access · goldAbstract read
In one paragraph

Article in Diabetology & metabolic syndrome, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
4.0field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 42 citations in OpenAlex.

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  12. Role of visfatin in obesity-induced insulin resistance.World journal of clinical cases · 2022
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  13. Article
  14. Sex Differences in Adiposity and Cardiovascular Diseases.International journal of molecular sciences · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Long-Yi Zheng1Department of Endocrinology, Changhai Hospital, Second Military Medical University, 168 Changhai Road, Shanghai, 200433 China.
Xia Xu2Department of Rheumatology and Immunology, Changhai Hospital, Second Military Medical University, 168 Changhai Road, Shanghai, 200433 China.
Ren-Hui Wan1Department of Endocrinology, Changhai Hospital, Second Military Medical University, 168 Changhai Road, Shanghai, 200433 China.
Sheng Xia1Department of Endocrinology, Changhai Hospital, Second Military Medical University, 168 Changhai Road, Shanghai, 200433 China.
Jin Lu1Department of Endocrinology, Changhai Hospital, Second Military Medical University, 168 Changhai Road, Shanghai, 200433 China.
Qin Huang1Department of Endocrinology, Changhai Hospital, Second Military Medical University, 168 Changhai Road, Shanghai, 200433 China.
Changhai Hospital · CNSecond Military Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundVisfatin is a multifaceted protein that plays an important role in regulating a variety of physiological and pathological processes, including obesity, diabetes and cardiovascular disease. However, circulating visfatin levels in atherosclerosis plaque progression in patients with type 2 diabetes, or its association with the vascular territory affected remain unclear.

methodsWe evaluated the relationship between visfatin levels and carotid or femoral artery atherosclerosis in Chinese patients with type 2 diabetes. Serum levels of visfatin were measured by enzyme-linked immunosorbent assay (ELISA) in 97 inpatients with type 2 diabetes. Carotid and/or femoral atherosclerotic plaques were detected by B-mode ultrasound.

resultsSerum visfatin levels were elevated in the group with atherosclerotic plaques compared to the control group without plaques [0.68 (0.46-1.58) versus 0.45 (0.23-0.76) ng/mL, respectively,

conclusionsIn conclusion, among patients with T2DM, serum visfatin levels were elevated in those with atherosclerotic plaques, especially in patients with carotid atherosclerotic plaques. Serum visfatin may serve as a predictor of atherosclerotic plaques in patients with T2DM.

Indexed as

AtherosclerosisCarotid plaquesType 2 diabetes mellitusVisfatin

Identifiers

PMID31367237
PMCPMC6657107
OpenAlexW2964167336

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.