ReviewNature2019
Memory editing from science fiction to clinical practice.
Review in Nature, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 64 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
64 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- The recovery and retraction of memories of abuse: a scoping review.Frontiers in psychology · 2025Pooled it
- A systematic review and meta-analysis of experimental methods for modulating intrusive memories following lab-analogue trauma exposure in non-clinical populations.Nature human behaviour · 2024Pooled it
- Impaired learning, memory, and extinction in posttraumatic stress disorder: translational meta-analysis of clinical and preclinical studies.Translational psychiatry · 2023Pooled it
- Effects of doxycycline on intrusive experimental trauma memory: a pre-registered, randomized double-blind placebo-controlled trial.Translational psychiatry · 2026Trial
- Attenuating human fear memory retention with minocycline: a randomized placebo-controlled trial.Translational psychiatry · 2024Trial
- Circuit-informed modulation of traumatic memory in PTSD: integrating extinction, suppression, and reconsolidation.Molecular psychiatry · 2026Review
- Adaptive and Maladaptive Networks Using Ecological Momentary Assessment.Clinical psychology in Europe · 2026Article
- Forgetting as an active process: Attentional withdrawal following a forget instruction.Memory & cognition · 2026Article
- Neurovictimology and the risks of neurotechnologies and artificial intelligence: a forensic and legal perspective.Frontiers in psychology · 2026Article
- The cognitive neuroscience of memory representations.Neuroscience and biobehavioral reviews · 2025Review
- Targeting memory of embedded positive verbal content indirectly modulates negative visual memory.iScience · 2025Article
- Mechanisms of Change in Exposure Therapy for Anxiety and Related Disorders: A Research Agenda.Clinical psychological science : a journal of the Association for Psychological Science · 2025Article
- How Fear Memory is Updated: From Reconsolidation to Extinction?Neuroscience bulletin · 2025Review
- Application of peer-assisted learning under the LSPPDM mode in resident clinical skill training.BMC medical education · 2025Article
- Going Beyond Trauma: A Scoping Review on the Prevalence of Symptom-Relevant Negative Autobiographical Memories in Anxiety Disorders and Obsessive-Compulsive Disorder.Clinical psychology : a publication of the Division of Clinical Psychology of the American Psychological Association · 2025Article
- Emotion Regulation Under Stress: A Social Processing and Memory Perspective.Current topics in behavioral neurosciences · 2025Review
- Oxytocin does not impact forced-choice recognition memory in an experimental trauma film paradigm with healthy women.Frontiers in psychiatry · 2025Article
- How tapping works: physiological and psychological mechanisms in energy psychology.Frontiers in psychology · 2025Review
- Research Review: Why do prospective and retrospective measures of maltreatment differ? A narrative review.Journal of child psychology and psychiatry, and allied disciplines · 2024Review
- Recurrent negative autobiographical memories and mental health.Journal of mood and anxiety disorders · 2024Article
4 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Science fiction notions of altering problematic memories are starting to become reality as techniques emerge through which unique memories can be edited. Here we review memory-editing research with a focus on improving the treatment of psychopathology. Studies highlight two windows of memory vulnerability: initial storage, or consolidation; and re-storage after retrieval, or reconsolidation. Techniques have been identified that can modify memories at each stage, but translating these methods from animal models to humans has been challenging and implementation into clinical therapies has produced inconsistent benefits. The science of memory editing is more complicated and nuanced than fiction, but its rapid development holds promise for future applications.
Indexed as
Identifiers
31367027What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.