Evidence map›Paper›PMID 31366983›Full record

ArticleScientific reports2019

Quantifying Microsecond Exchange in Large Protein Complexes with Accelerated Relaxation Dispersion Experiments in the Solid State.

Carl Öster, Simone Kosol, Józef R Lewandowski

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 32 citations in OpenAlex.

  1. Article
  2. AcceleratedMagnetic resonance (Gottingen, Germany) · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Microsecond Motion of the Bacterial Transporter EmrE in Lipid Bilayers.Journal of the American Chemical Society · 2023
    Article
  10. Slice & Dice: nested spin-lattice relaxation measurements.Physical chemistry chemical physics : PCCP · 2023
    Article
  11. Review
  12. Chemical reviews · 2022
    Review
  13. Article
  14. Atomic-resolution chemical characterization of (2x)72-kDa tryptophan synthase via four- and five-dimensionalProceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  15. Article
  16. Model-Free or Not?Frontiers in molecular biosciences · 2021
    Review
  17. Dipolar Order Parameters in Large Systems With Fast Spinning.Frontiers in molecular biosciences · 2021
    Article
  18. Article
  19. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Carl ÖsterDepartment of Chemistry, University of Warwick, Gibbet Hill Road, Coventry, CV4 7AL, UK.ORCID http://orcid.org/0000-0002-8723-4533
Simone KosolDepartment of Chemistry, University of Warwick, Gibbet Hill Road, Coventry, CV4 7AL, UK.ORCID http://orcid.org/0000-0001-7913-4818
Józef R LewandowskiDepartment of Chemistry, University of Warwick, Gibbet Hill Road, Coventry, CV4 7AL, UK. j.r.lewandowski@warwick.ac.uk.ORCID http://orcid.org/0000-0001-6525-7083
University of Warwick · GB

Funding

Resource for Biocomputing Visualization and InformaticsP41GM103311 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI FERRIN, THOMAS E · 2012 to 2017
$8.2M
ChimeraX -- Next Generation Visualization and Analysis Software for Multiscale ModelingR01GM129325 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI FERRIN, THOMAS E · 2018 to 2025
$5.2M
Biotechnology and Biological Sciences Research Council BB/L022761/1Biotechnology and Biological Sciences Research Council BB/R010218/1NIGMS NIH HHS P41 GM103311NIGMS NIH HHS R01 GM129325
6 · The paper itself

Abstract

Solid state NMR is a powerful method to obtain information on the structure and dynamics of protein complexes that, due to solubility and size limitations, cannot be achieved by other methods. Here, we present an approach that allows the quantification of microsecond conformational exchange in large protein complexes by using a paramagnetic agent to accelerate

Indexed as

HumansImmunoglobulin GMotionNuclear Magnetic Resonance, BiomolecularProtein Conformation, alpha-HelicalProtein Conformation, beta-StrandProteinsImmunoglobulin GProteins

Identifiers

PMID31366983
PMCPMC6668460
OpenAlexW2966244536

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.