ArticleScientific reports2019
Parallel Fourier ptychographic microscopy for high-throughput screening with 96 cameras (96 Eyes).
Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 67 citations in OpenAlex.
- Fourier ptychography microscopy for digital pathology.Journal of microscopy · 2025Review
- ST-FPM: suppressor tunable FPM for high-quality and highly robust full-field reconstruction.Biomedical optics express · 2025Article
- Rapid 3D imaging at cellular resolution for digital cytopathology with a multi-camera array scanner (MCAS).Npj imaging · 2024Article
- Deep-ultraviolet Fourier ptychography (DUV-FP) for label-free biochemical imaging via feature-domain optimization.APL photonics · 2024Article
- Long-term imaging of three-dimensional hyphal development using the ePetri dish.Biomedical optics express · 2024Article
- Review
- ComplexEye: a multi-lens array microscope for high-throughput embedded immune cell migration analysis.Nature communications · 2023Article
- Spatial- and Fourier-domain ptychography for high-throughput bio-imaging.Nature protocols · 2023Review
- Implementation of miniaturized modular-array fluorescence microscopy for long-term live-cell imaging.Applied optics · 2023Article
- Optical ptychography for biomedical imaging: recent progress and future directions [Invited].Biomedical optics express · 2023Review
- Automating the High-Throughput Screening of Protein-Based Optical Indicators and Actuators.Biochemistry · 2023Review
- Implementation of free-space Fourier Ptychography with near maximum system numerical aperture.Optics express · 2022Article
- Article
- Cellular analysis using label-free parallel array microscopy with Fourier ptychography.Biomedical optics express · 2022Article
- Robust Fourier ptychographic microscopy via a physics-based defocusing strategy for calibrating angle-varied LED illumination.Biomedical optics express · 2022Article
- Review of bio-optical imaging systems with a high space-bandwidth product.Advanced photonics · 2021Article
- Miniaturized modular-array fluorescence microscopy.Biomedical optics express · 2020Article
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We report the implementation of a parallel microscopy system (96 Eyes) that is capable of simultaneous imaging of all wells on a 96-well plate. The optical system consists of 96 microscopy units, where each unit is made out of a four element objective, made through a molded injection process, and a low cost CMOS camera chip. By illuminating the sample with angle varying light and applying Fourier Ptychography, we can improve the effective brightfield imaging numerical aperture of the objectives from 0.23 to 0.3, and extend the depth of field from ±5 μm to ±15 μm. The use of Fourier Ptychography additionally allows us to computationally correct the objectives' aberrations out of the rendered images, and provides us with the ability to render phase images. The 96 Eyes acquires raw data at a rate of 0.7 frame per second (all wells) and the data are processed with 4 cores of graphical processing units (GPUs; GK210, Nvidia Tesla K80, USA). The system is also capable of fluorescence imaging (excitation = 465 nm, emission = 510 nm) at the native resolution of the objectives. We demonstrate the capability of this system by imaging S1P
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.