Evidence map›Paper›PMID 31366904›Full record

ArticleCell death & disease2019

GLI1 activation by non-classical pathway integrin α

Hui Dong, Hongchang Liu, Wen Zhou, Fan Zhang, Chuan Li, Jun Chen, Chenjun Tan, Bo Tang, Peiwu Yu

Open access · goldAbstract read
In one paragraph

Article in Cell death & disease, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Review
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Roles of Integrins in Gastrointestinal Cancer Metastasis.Frontiers in molecular biosciences · 2021
    Review
  17. Article
  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Hui DongDepartment of General Surgery, Center of Minimal Invasive Gastrointestinal Surgery, Southwest Hospital, Army Medical University (Third Military Medical University), 400038, Chongqing, China.
Hongchang LiuDepartment of General Surgery, Center of Minimal Invasive Gastrointestinal Surgery, Southwest Hospital, Army Medical University (Third Military Medical University), 400038, Chongqing, China.
Wen ZhouDepartment of Biological Sciences, Columbia University, New York, NY, 10027, USA.
Fan ZhangDepartment of General Surgery, Center of Minimal Invasive Gastrointestinal Surgery, Southwest Hospital, Army Medical University (Third Military Medical University), 400038, Chongqing, China.
Chuan LiDepartment of General Surgery, Center of Minimal Invasive Gastrointestinal Surgery, Southwest Hospital, Army Medical University (Third Military Medical University), 400038, Chongqing, China.
Jun ChenDepartment of General Surgery, Center of Minimal Invasive Gastrointestinal Surgery, Southwest Hospital, Army Medical University (Third Military Medical University), 400038, Chongqing, China.
Chenjun TanDepartment of General Surgery, Center of Minimal Invasive Gastrointestinal Surgery, Southwest Hospital, Army Medical University (Third Military Medical University), 400038, Chongqing, China.
Bo TangDepartment of General Surgery, Center of Minimal Invasive Gastrointestinal Surgery, Southwest Hospital, Army Medical University (Third Military Medical University), 400038, Chongqing, China. tangtbo@sina.cn.
Peiwu YuDepartment of General Surgery, Center of Minimal Invasive Gastrointestinal Surgery, Southwest Hospital, Army Medical University (Third Military Medical University), 400038, Chongqing, China. yupeiwu01@sina.com.
Army Medical University · CNSouthwest Hospital · CNColumbia University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Peritoneal metastasis is one of the most important causes of postoperative death in patients with gastric cancer, and the exact mechanism remains unclear. The proliferation of multicellular aggregates of exfoliated malignant gastric cells in the abdominal cavity is the focus of current research. However, the mechanism how gastric cancer multicellular aggregates survive remains unclear. In this study, we demonstrated that multicellular aggregates of exfoliated gastric cancer cells in the abdominal cavity expressed a stem cell-Like phenotype. We found that Integrin α

Indexed as

AgedCell AggregationCell MovementCell ProliferationFemaleHumansIntegrin alphaVbeta3MaleMAP Kinase Signaling SystemMiddle AgedNeoplasm MetastasisNeoplastic Stem CellsPeritoneal NeoplasmsSignal TransductionStomach NeoplasmsZinc Finger Protein GLI1GLI1 protein, humanIntegrin alphaVbeta3Zinc Finger Protein GLI1

Identifiers

PMID31366904
PMCPMC6668446
OpenAlexW2966787235

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.