Evidence map›Paper›PMID 31366719›Full record

ArticlePlant physiology2019

LSD1-LIKE1-Mediated H3K4me2 Demethylation Is Required for Homologous Recombination Repair.

Takeshi Hirakawa, Keiko Kuwata, Maria E Gallego, Charles I White, Mika Nomoto, Yasuomi Tada, Sachihiro Matsunaga

Open access · greenAbstract read
In one paragraph

Article in Plant physiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 20 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Genome Maintenance Mechanisms at the Chromatin Level.International journal of molecular sciences · 2021
    Review
  8. TwoFrontiers in plant science · 2021
    Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Takeshi HirakawaDepartment of Applied Biological Science, Faculty of Science and Technology, Tokyo University of Science, 2641 Yamazaki, Noda, Chiba 278-8510, Japan.
Keiko KuwataInstitute of Transformative Bio-Molecules, Nagoya University, Nagoya 464-8601, Japan.
Maria E GallegoGénétique, Reproduction et Développement, Unité de Mixte de Recherche, Centre National de la Recherche Scientifique 6293, Clermont Université, Institut National de la Santé et de la Recherche Médicale U1103, Université Clermont Auvergne, F-63000 Clermont-Ferrand, France.ORCID 0000-0001-5588-9116
Charles I WhiteGénétique, Reproduction et Développement, Unité de Mixte de Recherche, Centre National de la Recherche Scientifique 6293, Clermont Université, Institut National de la Santé et de la Recherche Médicale U1103, Université Clermont Auvergne, F-63000 Clermont-Ferrand, France.ORCID 0000-0001-8152-5797
Mika NomotoCenter for Gene Research, Nagoya University, Nagoya 464-8602, Japan.
Yasuomi TadaCenter for Gene Research, Nagoya University, Nagoya 464-8602, Japan.ORCID 0000-0001-9900-069X
Sachihiro MatsunagaDepartment of Applied Biological Science, Faculty of Science and Technology, Tokyo University of Science, 2641 Yamazaki, Noda, Chiba 278-8510, Japan sachi@rs.tus.ac.jp.ORCID 0000-0003-3024-3559
Nagoya University · JPInserm · FRTokyo University of Science · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Homologous recombination is a key process for maintaining genome integrity and diversity. In eukaryotes, the nucleosome structure of chromatin inhibits the progression of homologous recombination. The DNA repair and recombination protein RAD54 alters the chromatin structure via nucleosome sliding to enable homology searches. For homologous recombination to progress, appropriate recruitment and dissociation of RAD54 is required at the site of homologous recombination; however, little is known about the mechanism regulating RAD54 dynamics in chromatin. Here, we reveal that the histone demethylase LYSINE-SPECIFIC DEMETHYLASE1-LIKE 1 (LDL1) regulates the dissociation of RAD54 at damaged sites during homologous recombination repair in the somatic cells of Arabidopsis (

Indexed as

Recombinational DNA RepairArabidopsisArabidopsis ProteinsDNA HelicasesHistone DemethylasesHistonesArabidopsis ProteinsAT1G62830 protein, ArabidopsisDNA HelicasesHistone DemethylasesHistonesRAD54 protein, Arabidopsis

Identifiers

PMID31366719
PMCPMC6776857
OpenAlexW2965091629

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.