Evidence map›Paper›PMID 31366710›Full record

ArticlemSphere2019

The Glycosylphosphatidylinositol-Anchored

Laetitia Muszkieta, Thierry Fontaine, Rémi Beau, Isabelle Mouyna, Marian Samuel Vogt, Jonathan Trow, Brendan P Cormack, Lars-Oliver Essen, Gregory Jouvion, Jean-Paul Latgé

Open access · goldAbstract read
In one paragraph

Article in mSphere, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
6.4field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 36 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Properties of Putative APSES Transcription Factor AfpA inJournal of fungi (Basel, Switzerland) · 2025
    Article
  5. A Novel CFEM Effector inInternational journal of molecular sciences · 2025
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Conidium Specific Polysaccharides inJournal of fungi (Basel, Switzerland) · 2023
    Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Transcriptomic and Ultrastructural Analyses ofFrontiers in microbiology · 2021
    Article
  18. Article
  19. Article
  20. Galactomannan Produced byJournal of fungi (Basel, Switzerland) · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 3 countries.

Laetitia MuszkietaUnité des Aspergillus, Institut Pasteur, Paris, France.
Thierry FontaineUnité des Aspergillus, Institut Pasteur, Paris, France thierry.fontaine@pasteur.fr jean-paul.latge@pasteur.fr.
Rémi BeauUnité des Aspergillus, Institut Pasteur, Paris, France.
Isabelle MouynaUnité des Aspergillus, Institut Pasteur, Paris, France.
Marian Samuel VogtFaculty of Chemistry, Philipps-Universität Marburg, Marburg, Germany.
Jonathan TrowDepartment of Molecular Biology and Genetics, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Brendan P CormackDepartment of Molecular Biology and Genetics, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Lars-Oliver EssenFaculty of Chemistry, Philipps-Universität Marburg, Marburg, Germany.
Gregory JouvionHistopathologie humaine et modèles animaux, Institut Pasteur, Paris, France.
Jean-Paul LatgéUnité des Aspergillus, Institut Pasteur, Paris, France thierry.fontaine@pasteur.fr jean-paul.latge@pasteur.fr.
Institut Pasteur · FRJohns Hopkins Medicine · USPhilipps University of Marburg · DE

Funding

AIDS Opportunistic Pathogens/Fungal Cell Wall Drug TargetsR21DE017085 · NIDCR · JOHNS HOPKINS UNIVERSITY · PI CORMACK, BRENDAN · 2005 to 2006
$403k
NIDCR NIH HHS R21 DE017085
6 · The paper itself

Abstract

The fungal cell wall is a complex and dynamic entity essential for the development of fungi. It is composed mainly of polysaccharides that are synthetized by protein complexes. At the cell wall level, enzyme activities are involved in postsynthesis polysaccharide modifications such as cleavage, elongation, branching, and cross-linking. Glycosylphosphatidylinositol (GPI)-anchored proteins have been shown to participate in cell wall biosynthesis and specifically in polysaccharide remodeling. Among these proteins, the DFG family plays an essential role in controlling polar growth in yeast. In the filamentous fungus and opportunistic human pathogen

Indexed as

Aspergillus fumigatusbeta-GlucansCell WallChitinFungal ProteinsGalactoseGene DeletionGlycosylphosphatidylinositolsMannansProteoglycansVirulencebeta-GlucansChitinFungal ProteinsgalactomannanGalactoseGlycosylphosphatidylinositolsMannanspolysaccharide-KProteoglycansAspergillus fumigatuscell wallglycobiology

Identifiers

PMID31366710
PMCPMC6669337
OpenAlexW2964585387

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.