Evidence map›Paper›PMID 31366666›Full record

ArticleThe Journal of cell biology2019

Chromatin targeting of nuclear pore proteins induces chromatin decondensation.

Terra M Kuhn, Pau Pascual-Garcia, Alejandro Gozalo, Shawn C Little, Maya Capelson

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of cell biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 53 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Nuclear transport proteins: structure, function, and disease relevance.Signal transduction and targeted therapy · 2023
    Review
  12. Review
  13. Review
  14. eLife · 2023
    Article
  15. Article
  16. Article
  17. The Nuclear Pore Complex as a Transcription Regulator.Cold Spring Harbor perspectives in biology · 2022
    Review
  18. Article
  19. Evolution and diversification of the nuclear pore complex.Biochemical Society transactions · 2021
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Terra M KuhnDepartment of Cell and Developmental Biology, Penn Institute of Epigenetics, University of Pennsylvania, Philadelphia, PA.
Pau Pascual-GarciaDepartment of Cell and Developmental Biology, Penn Institute of Epigenetics, University of Pennsylvania, Philadelphia, PA.ORCID 0000-0002-7482-4251
Alejandro GozaloDepartment of Cell and Developmental Biology, Penn Institute of Epigenetics, University of Pennsylvania, Philadelphia, PA.
Shawn C LittleDepartment of Cell and Developmental Biology, Penn Institute of Epigenetics, University of Pennsylvania, Philadelphia, PA.ORCID 0000-0002-2815-3696
Maya CapelsonDepartment of Cell and Developmental Biology, Penn Institute of Epigenetics, University of Pennsylvania, Philadelphia, PA capelson@pennmedicine.upenn.edu.ORCID 0000-0002-1695-316X
University of Pennsylvania · US

Funding

Graduate Training in Developmental BiologyT32HD083185 · NICHD · UNIVERSITY OF PENNSYLVANIA · PI Michael Granato, Foteini Mourkioti · 2015 to 2026
$4.0M
Nuclear Pore Complexes As Scaffolds For Genome Architecture And Epigenetic MaintenanceR01GM124143 · NIGMS · UNIVERSITY OF PENNSYLVANIA · PI CAPELSON, MAYA · 2017 to 2025
$3.0M
NICHD NIH HHS T32 HD083185NIGMS NIH HHS R01 GM124143
6 · The paper itself

Abstract

Nuclear pore complexes have emerged in recent years as chromatin-binding nuclear scaffolds, able to influence target gene expression. However, how nucleoporins (Nups) exert this control remains poorly understood. Here we show that ectopically tethering

Indexed as

AnimalsChromatin Assembly and DisassemblyDrosophila melanogasterDrosophila ProteinsNuclear PoreNuclear Pore Complex ProteinsDrosophila ProteinsNuclear Pore Complex ProteinsSEC13 protein, Drosophila

Identifiers

PMID31366666
PMCPMC6719443
OpenAlexW2966316935

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.