Evidence map›Paper›PMID 31366619›Full record

ArticleBlood2019

High frequency of inactivating tetraspanin

Suraya Elfrink, Charlotte M de Winde, Michiel van den Brand, Madeleine Berendsen, Margaretha G M Roemer, Frank Arnold, Luuk Janssen, Alie van der Schaaf, Erik Jansen, Patricia J T A Groenen and 12 more

Open access · bronzeAbstract read
In one paragraph

Article in Blood, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 22 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Role of RNA Splicing Mutations in Diffuse Large B Cell Lymphoma.International journal of general medicine · 2023
    Review
  5. Article
  6. Article
  7. Review
  8. Article
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  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors at 4 institutions in 1 country.

Suraya ElfrinkDepartment of Tumor Immunology and.
Charlotte M de WindeDepartment of Tumor Immunology and.ORCID 0000-0002-8318-4612
Michiel van den BrandDepartment of Pathology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, The Netherlands.ORCID 0000-0001-8871-6254
Madeleine BerendsenDepartment of Pathology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, The Netherlands.
Margaretha G M RoemerAmsterdam UMC-Vrije Universiteit Amsterdam, Department of Pathology and Cancer Center Amsterdam, Amsterdam, The Netherlands.
Frank ArnoldDepartment of Tumor Immunology and.
Luuk JanssenDepartment of Tumor Immunology and.
Alie van der SchaafDepartment of Tumor Immunology and.
Erik JansenDepartment of Tumor Immunology and.
Patricia J T A GroenenDepartment of Pathology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, The Netherlands.ORCID 0000-0003-4314-228X
Astrid EijkelenboomDepartment of Pathology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, The Netherlands.ORCID 0000-0001-8264-8131
Wendy StevensDepartment of Hematology, Radboud University Medical Center, Nijmegen, The Netherlands.
Corine J HessDepartment of Hematology, Radboud University Medical Center, Nijmegen, The Netherlands.
J Han van KriekenDepartment of Pathology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, The Netherlands.ORCID 0000-0002-8105-0450
Joost S P VermaatDepartment of Hematology and.
Arjen H G ClevenDepartment of Pathology, Leiden University Medical Center, Leiden, The Netherlands; and.
Ruben A L de GroenDepartment of Hematology and.
Viviana NevianiCrystal and Structural Chemistry, Department of Chemistry, Bijvoet Center for Biomolecular Research, Utrecht University, Utrecht, The Netherlands.ORCID 0000-0002-5729-3639
Daphne de JongAmsterdam UMC-Vrije Universiteit Amsterdam, Department of Pathology and Cancer Center Amsterdam, Amsterdam, The Netherlands.ORCID 0000-0002-9725-4060
Sjoerd van DeventerDepartment of Tumor Immunology and.
Blanca ScheijenDepartment of Pathology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, The Netherlands.
Annemiek B van SprielDepartment of Tumor Immunology and.ORCID 0000-0002-3590-2368
Radboud University Nijmegen · NLAmsterdam University Medical Centers · NLLeiden University Medical Center · NLUtrecht University · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tetraspanin CD37 is predominantly expressed on the cell surface of mature B lymphocytes and is currently being studied as novel therapeutic target for B-cell lymphoma. Recently, we demonstrated that loss of CD37 induces spontaneous B-cell lymphoma in

Indexed as

Immune PrivilegeAntigens, NeoplasmCentral Nervous SystemCentral Nervous System NeoplasmsCohort StudiesDNA Mutational AnalysisFemaleGene FrequencyGene SilencingHumansLymphoma, Large B-Cell, DiffuseMaleMutationTesticular NeoplasmsTestisTetraspaninsAntigens, NeoplasmCD37 protein, humanTetraspanins

Identifiers

PMID31366619
PMCPMC6789512
OpenAlexW2964658727

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.