Evidence map›Paper›PMID 31366456›Full record

GuidelineGut2019

British Society of Gastroenterology guidelines for oesophageal manometry and oesophageal reflux monitoring.

Nigel J Trudgill, Daniel Sifrim, Rami Sweis, Mark Fullard, Kumar Basu, Mimi McCord, Michael Booth, John Hayman, Guy Boeckxstaens, Brian T Johnston and 2 more

Registry-linked trialAbstract readPractice Guideline
In one paragraph

Guideline in Gut, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05238636 (The Effect of Anti-reflux Procedures), which is not on this map. Cited by 41 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05238636 unknown statusnot on this mapstarted 2022, after this paper: background citation

The Effect of Anti-reflux Procedures (Stretta, LINX, and Fundoplication) on Physiological Parameters Contributing to Symptom Resolution in Adults With Gastro-oesophageal Reflux at a Single UK Tertiary Centre

TypeobservationalSponsorSt George's, University of LondonRan2022 to 2024Enrolled60ConditionsGastroesophageal RefluxArmsAnti-reflux surgery - Stretta procedure or LINX device or laparoscopic fundoplication
3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Guideline
  3. Observational
  4. Utilization trends for esophageal motility testing in the United States.Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus · 2026
    Article
  5. Article
  6. Review
  7. Impact of referral delays on dysphagia outcomes in a Saudi tertiary center.World journal of gastrointestinal endoscopy · 2025
    Article
  8. Article
  9. Article
  10. Insight into global burden of gastroesophageal reflux disease: Understanding its reach and impact.World journal of gastrointestinal pharmacology and therapeutics · 2025
    Review
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Results of the ARROW survey of anti-reflux practice in the United Kingdom.Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus · 2023
    Article
  17. Review
  18. Review
  19. Article
  20. Effects of acids, pepsin, bile acids, and trypsin on laryngopharyngeal reflux diseases: physiopathology and therapeutic targets.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Nigel J TrudgillSandwell and West Birmingham Hospitals NHS Trust, West Bomwich, UK.ORCID 0000-0002-8040-8158
Daniel SifrimCentre of Gastroenterology Research, Queen Mary University London, London, UK.
Rami SweisUniversity College London Hospitals NHS Foundation Trust, London, UK.
Mark FullardWest Hertfordshire Hospitals NHS Trust, Watford, Hertfordshire, UK.
Kumar BasuSheffield Teaching Hospitals NHS Foundation Trust, Sheffield, UK.
Mimi McCordHeartburn Cancer UK, Baingstoke, UK.
Michael BoothRoyal Berkshire NHS Foundation Trust, Reading, UK.
John HaymanSandwell and West Birmingham Hospitals NHS Trust, West Bromwich, UK.
Guy BoeckxstaensGastroenterology, University Hospital, KU Leuven, Leuven, Belgium.
Brian T JohnstonDepartment of Gastroenterology, Belfast Health and Social Care Trust, Belfast, UK.
Nicola AgerSandwell and West Birmingham Hospitals NHS Trust, West Bromwich, UK.
John De CaesteckerUniversity Hospitals of Leicester NHS Trust, Leicester, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

These guidelines on oesophageal manometry and gastro-oesophageal reflux monitoring supersede those produced in 2006. Since 2006 there have been significant technological advances, in particular, the development of high resolution manometry (HRM) and oesophageal impedance monitoring. The guidelines were developed by a guideline development group of patients and representatives of all the relevant professional groups using the Appraisal of Guidelines for Research and Evaluation (AGREE II) tool. A systematic literature search was performed and the GRADE (Grading of Recommendations Assessment, Development and Evaluation) tool was used to evaluate the quality of evidence and decide on the strength of the recommendations made. Key strong recommendations are made regarding the benefit of: (i) HRM over standard manometry in the investigation of dysphagia and, in particular, in characterising achalasia, (ii) adjunctive testing with larger volumes of water or solids during HRM, (iii) oesophageal manometry prior to antireflux surgery, (iv) pH/impedance monitoring in patients with reflux symptoms not responding to high dose proton pump inhibitors and (v) pH monitoring in all patients with reflux symptoms responsive to proton pump inhibitors in whom surgery is planned, but combined pH/impedance monitoring in those not responsive to proton pump inhibitors in whom surgery is planned. This work has been endorsed by the Clinical Services and Standards Committee of the British Society of Gastroenterology (BSG) under the auspices of the oesophageal section of the BSG.

Indexed as

GastroenterologySocieties, MedicalGastroesophageal RefluxHumansManometryMonitoring, PhysiologicUnited Kingdommanometryoesophageal motility disorderoesophageal ph monitoringph monitoring

Identifiers

PMID31366456
PMCPMC6839728

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.