Evidence map›Paper›PMID 31366317›Full record

ArticleBMC neuroscience2019

Exploration of time-frequency reassignment and homologous inter-hemispheric asymmetry analysis of MCI-AD brain activity.

T Nimmy John, Puthankattil Subha Dharmapalan, N Ramshekhar Menon

Abstract read
In one paragraph

Article in BMC neuroscience, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
  6. EEG asymmetry and cognitive testing in MCI identification.International journal of psychophysiology : official journal of the International Organization of Psychophysiology · 2022
    Article
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

T Nimmy JohnDepartment of Electrical Engineering, National Institute of Technology Calicut, Calicut, Kerala, India. nimmijohnt@yahoo.co.in.ORCID 0000-0003-1869-367X
Puthankattil Subha DharmapalanDepartment of Electrical Engineering, National Institute of Technology Calicut, Calicut, Kerala, India.ORCID 0000-0001-9413-4955
N Ramshekhar MenonDepartment of Neurology, Sree Chitra Tirunal Institute for Medical Sciences and Technology, Trivandrum, Kerala, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn this study, nonlinear based time-frequency (TF) and time domain investigations are employed for the analysis of electroencephalogram (EEG) signals of mild cognitive impairment-Alzheimer's disease (MCI-AD) patients and healthy controls. This study attempts to comprehend the cognitive decline of MCI-AD under both resting and cognitive task conditions.

resultsWavelet-based synchrosqueezing transform (SST) alleviates the smearing of energy observed in the spectrogram around the central frequencies in short-time Fourier transform (STFT), and continuous wavelet transform (CWT). A precise TF representation is assured due to the reassignment of scale variable to the frequency variable. It is discerned from the studies of time domain measures encompassing fractal dimension (FD) and approximate entropy (ApEn), that the parietal lobe is the most affected in MCI-AD under both resting and cognitive states. Alterations in asymmetry in the brain hemispheres are analysed using the homologous areas inter-hemispheric symmetry (HArS).

conclusionTime and time-frequency domain analysis of EEG signals have been used for distinguishing various brain states. Therefore, EEG analysis is highly useful for the screening of AD in its prodromal phase.

Indexed as

AgedAged, 80 and overAlzheimer DiseaseCase-Control StudiesCognitive DysfunctionElectroencephalographyFemaleFunctional LateralityHumansMaleMiddle AgedWavelet AnalysisAlzheimer’s diseaseApproximate entropyElectroencephalographyFractal dimensionHArSSynchrosqueezing transform

Identifiers

PMID31366317
PMCPMC6670117

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.