Evidence map›Paper›PMID 31366127›Full record

ArticleMarine drugs2019

Cytotoxic and Antiproliferative Effects of Preussin, a Hydroxypyrrolidine Derivative from the Marine Sponge-Associated Fungus

Fernanda Malhão, Alice A Ramos, Suradet Buttachon, Tida Dethoup, Anake Kijjoa, Eduardo Rocha

Open access · goldAbstract read
In one paragraph

Article in Marine drugs, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
2.7field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it, 38 citations in OpenAlex.

  1. Pooled it
  2. Biomimetic Scaffold-Based 3D Models for Decoding Cancer Biology and Advancing Therapy.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Review
  3. Article
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  6. Review
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  8. Article
  9. Alternaria alternata (SDHY01/02), a fungus associated with Lamellodysidea herbacea: its anticancer potential and responsible constituent(s).International microbiology : the official journal of the Spanish Society for Microbiology · 2023
    Article
  10. Review
  11. Article
  12. A monograph ofStudies in mycology · 2022
    Article
  13. Review
  14. Genomic Analysis and Antimicrobial Components of M7, anJournal of fungi (Basel, Switzerland) · 2022
    Article
  15. Article
  16. Review
  17. Article
  18. Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Fernanda MalhãoInstitute of Biomedical Sciences Abel Salazar (ICBAS), Universidade do Porto (U.Porto), Rua de Jorge Viterbo Ferreira n 228, 4050-313 Porto, Portugal.ORCID 0000-0003-4978-5358
Alice A RamosInstitute of Biomedical Sciences Abel Salazar (ICBAS), Universidade do Porto (U.Porto), Rua de Jorge Viterbo Ferreira n 228, 4050-313 Porto, Portugal.
Suradet ButtachonInstitute of Biomedical Sciences Abel Salazar (ICBAS), Universidade do Porto (U.Porto), Rua de Jorge Viterbo Ferreira n 228, 4050-313 Porto, Portugal.ORCID 0000-0002-5134-0115
Tida DethoupDepartment of Plant Pathology, Faculty of Agriculture, Kasetsart University, Bangkok 10240, Thailand.
Anake KijjoaInstitute of Biomedical Sciences Abel Salazar (ICBAS), Universidade do Porto (U.Porto), Rua de Jorge Viterbo Ferreira n 228, 4050-313 Porto, Portugal.ORCID 0000-0002-3321-1061
Eduardo RochaInstitute of Biomedical Sciences Abel Salazar (ICBAS), Universidade do Porto (U.Porto), Rua de Jorge Viterbo Ferreira n 228, 4050-313 Porto, Portugal. erocha@icbas.up.pt.ORCID 0000-0001-9813-4389
Universidade do Porto · PTKasetsart University · TH

Funding

Fundação para a Ciência e a Tecnologia UUID/Multi/04423/2019
6 · The paper itself

Abstract

Preussin, a hydroxyl pyrrolidine derivative isolated from the marine sponge-associated fungus

Indexed as

AnimalsAnisomycinAntineoplastic AgentsAspergillusBreast NeoplasmsCell Culture TechniquesCell ProliferationCell SurvivalDrug Screening Assays, AntitumorFemaleHumansMCF-7 CellsPoriferaAnisomycinAntineoplastic Agentspreussin3D cell cultureantiproliferative activitybreast cancercytotoxic activitypreussin

Identifiers

PMID31366127
PMCPMC6722565
OpenAlexW2966648157

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.