Evidence map›Paper›PMID 31366089›Full record

ReviewCancers2019

PTEN Tumor-Suppressor: The Dam of Stemness in Cancer.

Francesca Luongo, Francesca Colonna, Federica Calapà, Sara Vitale, Micol E Fiori, Ruggero De Maria

Open access · goldAbstract readReview
In one paragraph

Review in Cancers, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 111 papers.

0numbers the graph read from it
0cells of the map it votes in
111citing papers in PubMed
7.1field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

111 citing papers in PubMed, 182 citations in OpenAlex.

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  13. PI3 K/AKT/mTOR pathway and its role in breast cancer stem cells.Naunyn-Schmiedeberg's archives of pharmacology · 2025
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51 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Francesca LuongoIstituto di Patologia Generale, Università Cattolica del Sacro Cuore, Largo Francesco Vito 1, 00168 Rome, Italy.
Francesca ColonnaIstituto di Patologia Generale, Università Cattolica del Sacro Cuore, Largo Francesco Vito 1, 00168 Rome, Italy.
Federica CalapàIstituto di Patologia Generale, Università Cattolica del Sacro Cuore, Largo Francesco Vito 1, 00168 Rome, Italy.ORCID 0000-0003-0701-968X
Sara VitaleIstituto di Patologia Generale, Università Cattolica del Sacro Cuore, Largo Francesco Vito 1, 00168 Rome, Italy.ORCID 0000-0002-9011-9042
Micol E FioriDepartment of Oncology and Molecular Medicine, Istituto Superiore di Sanità, 00161 Rome, Italy. fiorimicol@gmail.com.ORCID 0000-0002-1813-7035
Ruggero De MariaIstituto di Patologia Generale, Università Cattolica del Sacro Cuore, Largo Francesco Vito 1, 00168 Rome, Italy. ruggero.demaria@unicatt.it.
Università Cattolica del Sacro Cuore · ITIstituto Superiore di Sanità · IT

Funding

Associazione Italiana per la Ricerca sul Cancro 5x1000 Clinical Oncology Extension Program 9979
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

cancer stem cellsPTENtargeted therapytherapy resistance

Identifiers

PMID31366089
PMCPMC6721423
OpenAlexW2966296683

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.