Evidence map›Paper›PMID 31366075›Full record

ArticleMolecules (Basel, Switzerland)2019

Thyroid Peroxidase Activity is Inhibited by Phenolic Compounds-Impact of Interaction.

Ewa Habza-Kowalska, Agnieszka A Kaczor, Justyna Żuk, Dariusz Matosiuk, Urszula Gawlik-Dziki

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
1.3field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 57 citations in OpenAlex.

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  12. The mechanism and application ofFrontiers in endocrinology · 2025
    Review
  13. Article
  14. Quercetin and Thyroid.Antioxidants (Basel, Switzerland) · 2024
    Article
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  16. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Ewa Habza-KowalskaDepartment of Biochemistry and Food Chemistry, University of Life Sciences, Skromna Str. 8, 20-704 Lublin, Poland.
Agnieszka A KaczorDepartment of Synthesis and Chemical Technology of Pharmaceutical Substances, Faculty of Pharmacy with Division of Medical Analytics, Medical University of Lublin, 4A Chodzki St., PL-20093 Lublin, Poland.ORCID 0000-0001-8679-9623
Justyna ŻukDepartment of Synthesis and Chemical Technology of Pharmaceutical Substances, Faculty of Pharmacy with Division of Medical Analytics, Medical University of Lublin, 4A Chodzki St., PL-20093 Lublin, Poland.
Dariusz MatosiukDepartment of Synthesis and Chemical Technology of Pharmaceutical Substances, Faculty of Pharmacy with Division of Medical Analytics, Medical University of Lublin, 4A Chodzki St., PL-20093 Lublin, Poland.
Urszula Gawlik-DzikiDepartment of Biochemistry and Food Chemistry, University of Life Sciences, Skromna Str. 8, 20-704 Lublin, Poland. urszula.gawlik@up.lublin.pl.ORCID 0000-0002-7308-4335
Medical University of Lublin · PLUniversity of Life Sciences in Lublin · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this study was to estimate the mode of thyroid peroxidase (TPO) inhibition by polyphenols: Chlorogenic acid, rosmarinic acid, quercetin, and rutin. All the tested polyphenols inhibited TPO; the IC

Indexed as

Amino Acid MotifsAnimalsAntioxidantsBenzothiazolesCatalytic DomainChlorogenic AcidCinnamatesDepsidesEnzyme InhibitorsGene ExpressionIodide PeroxidaseIodidesKineticsMolecular Docking SimulationProtein BindingProtein Conformation, alpha-Helical2,2'-azino-di-(3-ethylbenzothiazoline)-6-sulfonic acidAntioxidantsBenzothiazolesChlorogenic AcidCinnamatesDepsidesEnzyme InhibitorsIodide PeroxidaseIodidesQuercetinRosmarinic AcidRutinSulfonic Acidsdietary polyphenolsinteractionsmolecular modelingthyroid peroxidase (TPO)

Identifiers

PMID31366075
PMCPMC6696198
OpenAlexW2965974056

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.