Evidence map›Paper›PMID 31366044›Full record

ArticleCells2019

Wnt Receptor Frizzled-4 as a Marker for Isolation of Enteric Neural Progenitors in Human Children.

Peter H Neckel, Melanie Scharr, Karin Seid, Katharina Nothelfer, Jörg Fuchs, Florian Obermayr, Bernhard Hirt, Stephan M Huber, Lothar Just

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cells, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact, top 86% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Peter H NeckelInstitute of Clinical Anatomy and Cell Analysis, University of Tübingen, 72074 Tübingen, Germany. peter.neckel@uni-tuebingen.de.
Melanie ScharrInstitute of Clinical Anatomy and Cell Analysis, University of Tübingen, 72074 Tübingen, Germany.
Karin SeidInstitute of Clinical Anatomy and Cell Analysis, University of Tübingen, 72074 Tübingen, Germany.
Katharina NothelferInstitute of Clinical Anatomy and Cell Analysis, University of Tübingen, 72074 Tübingen, Germany.
Jörg FuchsDepartment of Pediatric Surgery, University Children's Hospital, 72076 Tübingen, Germany.
Florian ObermayrDepartment of Pediatric Surgery, University Children's Hospital, 72076 Tübingen, Germany.
Bernhard HirtInstitute of Clinical Anatomy and Cell Analysis, University of Tübingen, 72074 Tübingen, Germany.
Stephan M HuberDepartment of Radiation Oncology, University of Tübingen, 72076 Tübingen, Germany.
Lothar JustInstitute of Clinical Anatomy and Cell Analysis, University of Tübingen, 72074 Tübingen, Germany.
University of Tübingen · DEUniversity Children's Hospital Tübingen · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Identification and isolation of neural progenitor cells from the human enteric nervous system (ENS) is currently hampered by the lack of reliable, specific markers. Here, we define the Wnt-receptor frizzled-4 as a marker for the isolation of enteric neural progenitor cells derived from paediatric gut samples. We show that the Wnt-receptor frizzled-4 is expressed in the human colon and in

Indexed as

BiomarkersCell Culture TechniquesCell DifferentiationCell ProliferationCells, CulturedCell SeparationChild, PreschoolColonEnteric Nervous SystemFemaleFlow CytometryFrizzled ReceptorsHumansInfantInfant, NewbornMaleBiomarkersFrizzled ReceptorsFZD4 protein, humanenteric nervous systemFACSfrizzledhuman stem cellsprogenitor cellsstem cell markerWnt

Identifiers

PMID31366044
PMCPMC6721585
OpenAlexW2965002701

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.