ArticleCell reports2019
Distinct Connectivity and Functionality of Aldehyde Dehydrogenase 1a1-Positive Nigrostriatal Dopaminergic Neurons in Motor Learning.
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Article in Cell reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers, 1 of them a synthesis that pooled it.
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55citing papers in PubMed, 1 pooled it
6.9field-weighted citation impact, top 2% of its field
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Who cites it
55 citing papers in PubMed, 1 synthesis or guideline pooled it, 89 citations in OpenAlex.
- Connectivity and Functionality of the Globus Pallidus Externa Under Normal Conditions and Parkinson's Disease.Frontiers in neural circuits · 2021Pooled it
- Calbindin stratifies midbrain dopaminergic neurons governing distinct aspects of locomotion.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Leucine-rich repeat kinase 2 impairs the release sites of Parkinson's disease vulnerable dopamine axons.Nature communications · 2026Article
- α-Synuclein pathology differentially alters T-type calcium currents in vulnerable and resilient substantia nigra dopaminergic subpopulations.bioRxiv : the preprint server for biology · 2026Article
- Sex-Dependent Effects of Glutamatergic Disruption on Dopaminergic Neuron Subtype Vulnerable in Parkinson's Disease.bioRxiv : the preprint server for biology · 2026Article
- ALDH2-mediated GABA biosynthesis regulates hippocampal LTP and learning adaptability.Nature chemical biology · 2026Article
- Developmental dopamine loss rewires striatal circuits to promote locomotion.Molecular neurodegeneration · 2026Article
- Whole-brain input organization ofFrontiers in neural circuits · 2026Article
- Recruitment of specific dopamine neuron sub-circuits by opioids.Addiction neuroscience · 2025Article
- Corticonigral projections recruit substantia nigra pars lateralis dopaminergic neurons for auditory threat memories.Nature communications · 2025Article
- Developmental Dopamine Loss Rewires Striatal Circuits to Promote Locomotion.Research square · 2025Article
- Progress in Disease-Modifying Therapies for Parkinson's Disease.Aging and disease · 2025Review
- Leucine-rich repeat kinase 2 impairs the release sites of Parkinson's disease vulnerable dopamine axons.bioRxiv : the preprint server for biology · 2025Article
- Parkinson's Disease-vulnerable and -resilient dopamine neurons display opposite responses to excitatory input.bioRxiv : the preprint server for biology · 2025Article
- Article
- Muscarinic Receptor Activation Preferentially Inhibits Rebound in Vulnerable Dopaminergic Neurons.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Molecularly distinct striatonigral neuron subtypes differentially regulate locomotion.Nature communications · 2025Article
- Subtype-specific roles of nigrostriatal dopaminergic neurons in motor and associative learning.Ageing and neurodegenerative diseases · 2025Article
- Building an action circuit with nigrostriatal dopaminergic neurons and striatonigral neurons.Handbook of behavioral neuroscience · 2025Article
- Nitrogen waste metabolism as a locus of nitrergic co-transmission in the brain.Frontiers in behavioral neuroscience · 2025Review
Corrections and comments
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Authors and funding
21 authors at 7 institutions in 2 countries.
Junbing WuTransgenic Section, Laboratory of Neurogenetics, National Institute on Aging, NIH, Bethesda, MD 20892, USA.
Justin KungTransgenic Section, Laboratory of Neurogenetics, National Institute on Aging, NIH, Bethesda, MD 20892, USA.
Jie DongTransgenic Section, Laboratory of Neurogenetics, National Institute on Aging, NIH, Bethesda, MD 20892, USA; Clinical Research Center on Neurological Diseases, First Affiliated Hospital, Dalian Medical University, Dalian 116011, P.R. China.
Lisa ChangTransgenic Section, Laboratory of Neurogenetics, National Institute on Aging, NIH, Bethesda, MD 20892, USA.
Chengsong XieTransgenic Section, Laboratory of Neurogenetics, National Institute on Aging, NIH, Bethesda, MD 20892, USA.
Ahsan HabibTransgenic Section, Laboratory of Neurogenetics, National Institute on Aging, NIH, Bethesda, MD 20892, USA.
Sarah HawesTransgenic Section, Laboratory of Neurogenetics, National Institute on Aging, NIH, Bethesda, MD 20892, USA.
Nannan YangTransgenic Section, Laboratory of Neurogenetics, National Institute on Aging, NIH, Bethesda, MD 20892, USA; National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, Hunan 410008, P.R. China.
Vivian ChenTransgenic Section, Laboratory of Neurogenetics, National Institute on Aging, NIH, Bethesda, MD 20892, USA.
Zhenhua LiuTransgenic Section, Laboratory of Neurogenetics, National Institute on Aging, NIH, Bethesda, MD 20892, USA; National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, Hunan 410008, P.R. China.
Rebekah EvansCellular Neurophysiology Unit, National Institute of Neurological Diseases and Stroke, NIH, Bethesda, MD 20892, USA.
Bo LiangNeural Engineering Unit, National Institute on Drug Abuse, NIH, Baltimore, MD 21224, USA.
Lixin SunTransgenic Section, Laboratory of Neurogenetics, National Institute on Aging, NIH, Bethesda, MD 20892, USA.
Jinhui DingComputational Biology Group, Laboratory of Neurogenetics, National Institute on Aging, NIH, Bethesda, MD 20892, USA.
Jia YuInstitute for Geriatrics and Rehabilitation, Beijing Geriatric Hospital, Beijing University of Chinese Medicine, Beijing 100095, P.R. China.
Sara Saez-AtienzarTransgenic Section, Laboratory of Neurogenetics, National Institute on Aging, NIH, Bethesda, MD 20892, USA.
Beisha TangNational Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, Hunan 410008, P.R. China.
Zayd KhaliqCellular Neurophysiology Unit, National Institute of Neurological Diseases and Stroke, NIH, Bethesda, MD 20892, USA.
Da-Ting LinNeural Engineering Unit, National Institute on Drug Abuse, NIH, Baltimore, MD 21224, USA.
Weidong LeClinical Research Center on Neurological Diseases, First Affiliated Hospital, Dalian Medical University, Dalian 116011, P.R. China.
Huaibin CaiTransgenic Section, Laboratory of Neurogenetics, National Institute on Aging, NIH, Bethesda, MD 20892, USA. Electronic address: caih@mail.nih.gov.
National Institute on Aging · USNational Institute of Neurological Disorders and Stroke · USNational Institute on Drug Abuse · USXiangya Hospital Central South University · CNBeijing University of Chinese Medicine · CNCentral South University · CNDalian Medical University · CN
Funding
Synaptic integration and intrinsic firing properties of basal ganglia neuronsZIANS003135 · NINDS · NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE · PI KHALIQ, ZAYD M · 2012 to 2025
$27.4MMolecular and Pathophysiological Study of Parkinson's DiseaseZIAAG000928 · NIA · NATIONAL INSTITUTE ON AGING · PI CAI, HUAIBIN · 2011 to 2025
$15.8MStriatal Projection Neuron Changes in Dopamine Depletion and Parkinsons DiseaseZIAAG000945 · NIA · NATIONAL INSTITUTE ON AGING · PI CAI, HUAIBIN · 2009 to 2025
$5.4MOKLAHOMA BIRTH DEFECTS REGISTRY IMPROVEMENT PROJECTU50DD000595 · DD · OKLAHOMA STATE DEPARTMENT OF HEALTH · PI VAZ, SHARON · 2010 to 2015
$1.1MDissecting the inhibitory architecture governing basal ganglia outputZIANS003172 · NINDS · NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE · PI KHALIQ, ZAYD M · 2019 to 2021
$196kIntramural NIH HHS Z99 AG999999NCBDD CDC HHS U50 DD000595
Abstract
Parkinson's disease causes the most profound loss of the aldehyde dehydrogenase 1A1-positive (ALDH1A1
Indexed as
LearningAldehyde Dehydrogenase 1 FamilyAnimalsCorpus StriatumDopamineDopaminergic NeuronsMiceMice, TransgenicRetinal DehydrogenaseSubstantia NigraAldehyde Dehydrogenase 1 FamilyALDH1A1 protein, mouseDopamineRetinal Dehydrogenasealdehyde dehydrogenase 1a1ALDH1A1brain mappingdopaminedopaminergic neuronsmotor skill learningParkinson’s diseasestriatumsubstantia nigra
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.