Evidence map›Paper›PMID 31365668›Full record

ReviewAnais brasileiros de dermatologia2019

Galectin 3: an extraordinary multifunctional protein in dermatology. Current knowledge and perspectives.

Efstathia Pasmatzi, Christina Papadionysiou, Alexandra Monastirli, George Badavanis, Dionysios Tsambaos

Open access · goldAbstract readReview
In one paragraph

Review in Anais brasileiros de dermatologia, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 3 countries.

Efstathia PasmatziDepartment of Dermatology, School of Medicine, Patras University, Rio-Patras, Greece.ORCID 0000-0003-0846-1752
Christina PapadionysiouDepartment of Dermatology, School of Medicine, Patras University, Rio-Patras, Greece.ORCID 0000-0002-1962-6615
Alexandra MonastirliDiscipline of Dermatology, Center for Dermatologic Diseases, Limassol, Cyprus.ORCID 0000-0003-4525-6766
George BadavanisDiscipline of Dermatology, Center for Dermatologic Diseases, Limassol, Cyprus.ORCID 0000-0002-9125-1280
Dionysios TsambaosDiscipline of Dermatology, Center for Dermatologic Diseases, Limassol, Cyprus.ORCID 0000-0003-1435-8030
American Society for Dermatologic Surgery · USUniversity of Patras · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Galectin 3 is a unique ~31 kDa protein that recognizes the N-acetyl-lactosamine structure of several glycoconjugates. It mainly occurs in epithelial and myeloid cells, but is also found in a variety of human cell types. In view of the crucial role played by galectin 3 in the regulation of cellular processes of essential importance and in the pathogenetic mechanisms of diverse disorders, it is not surprising that, particularly in the last three decades, the attention of the scientific community has been increasingly drawn to this extraordinary and multifunctional galectin. In this paper the authors summarize current knowledge on the expression of galectin 3 in normal and diseased human skin, its implications in the pathogenesis, diagnosis and prognosis of cutaneous disorders, and the perspectives of a novel approach to the treatment of the latter using galectin 3 or its inhibitors/antagonists.

Indexed as

Amino SugarsBlood ProteinsDermatitisGalectin 3GalectinsHumansAmino SugarsBlood ProteinsGalectin 3GalectinsLGALS3 protein, humanN-acetyllactosamine

Identifiers

PMID31365668
PMCPMC6668939
OpenAlexW2964770319

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.