Evidence map›Paper›PMID 31365445›Full record

ArticleThe Journal of cardiovascular nursing

Adverse-Event Free Survival, Hospitalizations, and Mortality in Left Ventricular Assist Device Recipients: A Rural-Urban Cohort Comparison.

Windy Alonso, Judith E Hupcey, Lisa Kitko, Bunny Pozehl, Kevin Kupzyk

Abstract readComparative Study
In one paragraph

Article in The Journal of cardiovascular nursing. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Observational
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Windy AlonsoWindy Alonso, PhD, RN Doctoral Student, The Pennsylvania State University, College of Nursing, Hershey. Judith E. Hupcey, EdD, CRNP, FAAN Associate Dean for Research and Professor, Nursing and Medicine, The Pennsylvania State University, College of Nursing, Hershey. Lisa Kitko, PhD, RN, FAHA, FAAN Associate Professor, The Pennsylvania State University, College of Nursing, University Park. Bunny Pozehl, PhD, APRN-NP, FHFSA, FAHA, FAAN Professor and Dorothy Hodges Olson Endowed Chair, University of Nebraska Medical Center, College of Nursing, Omaha. Kevin Kupzyk, PhD Assistant Professor, University of Nebraska Medical Center, College of Nursing, Omaha.
Judith E Hupcey
Lisa Kitko
Bunny Pozehl
Kevin Kupzyk

Funding

Identifying Disparities: Rural-Urban Comparison in Mechanical Circulatory SupportF31NR016895 · NINR · PENNSYLVANIA STATE UNIVERSITY, THE · PI ALONSO, WINDY WILLIAMS · 2016 to 2016
$31k
NINR NIH HHS F31 NR016895
6 · The paper itself

Abstract

backgroundThe number of individuals with advanced heart failure (HF) receiving left ventricular assist devices (LVADs) is growing. Postimplantation LVAD recipients return home to both rural and urban locations. The impact of rural or urban living on postimplantation outcomes has not been adequately explored.

objectiveThis cohort study examined adverse event-free survival, hospitalization-free survival, and all-cause mortality between rural and urban LVAD recipients in the first 2 years after implantation.

methodsData from LVAD recipients (N = 141) implanted at a single center in the northeastern United States were analyzed. Recipients of LVAD were designated as rural or urban by county of residence. Adverse events, hospitalizations, and survival time were examined using multivariate Cox proportional hazards models.

resultsThirty-seven percent of LVAD recipients in the cohort were rural. Two-thirds of all LVAD recipients experienced at least 1 adverse event (96/141, 68.1%). Although more urban recipients experienced adverse events, including death, rural versus urban models of both adverse events and survival were nonsignificant (adverse events: log-rank = 1.18, P = .28; hazard ratio [HR], 0.96; 95% confidence interval [CI], 0.57-1.63; P = .89; survival: log-rank =2.81, P = .09; HR, 0.45; 95% CI, 0.17-1.23; P = .12). Rural LVAD recipients experienced significantly more hospitalizations and shorter hospitalization-free survival (log-rank = 6.67, P = .009). However, the HR for survival was nonsignificant (HR, 1.5; 95% CI, 0.94-2.39; P = .08).

conclusionsFrequent adverse events and hospitalizations are of ongoing concern for LVAD recipients. More data are necessary to understand why urban LVAD recipients may experience shorter survival time compared with rural counterparts. Hospitalization may serve as a protective factor for rural LVAD recipients.

Indexed as

Heart-Assist DevicesAgedCohort StudiesDisease-Free SurvivalFemaleHeart FailureHospitalizationHumansMaleMiddle AgedProgression-Free SurvivalRural HealthUrban Health

Identifiers

PMID31365445
PMCPMC8381739

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.