Evidence map›Paper›PMID 31365344›Full record

ArticleEuropean journal of rheumatology2019

Survey on transportation and storage of biological therapies by patients.

Maira Arias Saavedra, Carolina Aimo, Jose Astudillo Andrade, Damaris Alvarez, Gabriel Sequeira, Eduardo Kerzberg

Abstract read
In one paragraph

Article in European journal of rheumatology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Maira Arias SaavedraDepartment of Rheumatology, Hospital J. M. Ramos Mejía, Buenos Aires, Argentina.ORCID http://orcid.org/0000-0001-6812-6898
Carolina AimoDepartment of Rheumatology, Hospital J. M. Ramos Mejía, Buenos Aires, Argentina.ORCID http://orcid.org/0000-0002-2846-4785
Jose Astudillo AndradeDepartment of Rheumatology, Hospital J. M. Ramos Mejía, Buenos Aires, Argentina.ORCID http://orcid.org/0000-0002-4023-4069
Damaris AlvarezDepartment of Rheumatology, Hospital J. M. Ramos Mejía, Buenos Aires, Argentina.ORCID http://orcid.org/0000-0003-1751-8386
Gabriel SequeiraDepartment of Rheumatology, Hospital J. M. Ramos Mejía, Buenos Aires, Argentina.ORCID http://orcid.org/0000-0003-0898-2224
Eduardo KerzbergDepartment of Rheumatology, Hospital J. M. Ramos Mejía, Buenos Aires, Argentina.ORCID http://orcid.org/0000-0002-5704-6777

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo assess key aspects of transportation and storage of biological therapies (BTs) on the part of the patients, from the time they collect them from the pharmacy up until the moment of administration.

methodsThis was a cross-sectional study in the form of a survey completed by outpatients older than 18 years who were administered BTs. The survey was carried out by the authors between August 2016 and January 2017.

resultsA total of 83 outpatients were interviewed (mean age, 53; standard deviation, 15; 76% female). Sixty percent had rheumatoid arthritis, 24% had psoriatic arthritis, and 16% sustained other rheumatic and inflammatory diseases. Twenty percent had not been informed of the importance of proper refrigeration when they were first prescribed BTs; 77% had acquired the medication at least 7 days before administration; 28% had misplaced the drug in the fridge (65% of them in the freezer); 90% was unaware of the temperature range at which the BT should be kept in the fridge, and only one (1%) of them had once used a thermometer to find out the fridge temperature. Fifty-three percent had suffered frequent power outages the previous summer, 22% had experienced blackouts longer than 48 hours; 37% had taken the BT to another house to avoid wasting it, and four (5%) patients had disposed of the drug due to a prolonged power outage.

conclusionUpon prescribing BTs, it is imperative that physicians brief patients on the relevance of suitable transportation and storage methods, and a treatment failure should prompt a thorough assessment of transportation and storage conditions.

Identifiers

PMID31365344
PMCPMC6467330

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