Evidence map›Paper›PMID 31364808›Full record

ArticleVeterinary ophthalmology2020

Equine infectious keratitis in Finland: Associated microbial isolates and susceptibility profiles.

Minna P Mustikka, Thomas S C Grönthal, Elina M Pietilä

Open access · hybridAbstract read
In one paragraph

Article in Veterinary ophthalmology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
2.2field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 30 citations in OpenAlex.

  1. Azole resistance inFrontiers in veterinary science · 2025
    Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Cold atmospheric plasma inactivatesJournal of medical microbiology · 2024
    Article
  8. Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Minna P MustikkaDepartment of Equine and Small Animal Medicine, University of Helsinki, Helsinki, Finland.ORCID https://orcid.org/0000-0002-7180-1660
Thomas S C GrönthalDepartment of Equine and Small Animal Medicine, University of Helsinki, Helsinki, Finland.ORCID https://orcid.org/0000-0001-8339-5818
Elina M PietiläDepartment of Equine and Small Animal Medicine, University of Helsinki, Helsinki, Finland.ORCID https://orcid.org/0000-0002-6281-163X
University of Helsinki · FI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo retrospectively describe laboratory findings, treatment, and outcome associated with equine infectious keratitis in Finland. ANIMALS AND PROCEDURES: Medical records of horses diagnosed with infectious keratitis in University of Helsinki Equine Hospital from January 2007 to June 2018 were reviewed.

resultsForty-seven cases were included. Keratomycosis was diagnosed in 27 eyes and bacterial keratitis in 20 eyes. Aspergillus flavus was the most frequent fungal isolate (9/17, 53%), followed by Cylindrocarpon sp. (3/17, 18%) and Aspergillus fumigatus (2/17, 12%). Susceptibility was tested for 10/11 Aspergillus sp. isolates; all were susceptible to voriconazole while only two were susceptible to amphotericin B. Cylindrocarpon sp. isolates were resistant to both agents. Streptococcus equi subsp. zooepidemicus was the most frequent bacterial isolate (9/19, 47%), followed by other streptococci (4/19, 21%). All 13 Streptococcus sp. isolates were susceptible to penicillin, and all tested isolates (n = 11) were also susceptible to chloramphenicol. Mean duration of medical treatment was longer in fungal keratitis (38 days) than in bacterial keratitis (25 days) (P < .001). Twenty-six of the eyes underwent globe-sparing surgery in addition to medical therapy. Recovery was achieved in 66% (31/47) of all cases and in 59% (16/27) and 75% (15/20) (P = .264) of cases with keratomycosis and bacterial keratitis, respectively.

conclusionsAlthough Aspergillus sp. and S zooepidemicus were the most frequently encountered isolates, cytology, culture, and susceptibility testing are essential to differentiate bacterial and fungal keratitis and guide the clinician to choose the most efficient treatment.

Indexed as

AnimalsAnti-Bacterial AgentsBacteriaBacterial InfectionsDrug Resistance, BacterialFemaleFinlandHorse DiseasesHorsesKeratitisMaleRetrospective StudiesAnti-Bacterial Agentsbacterial keratitiscorneaequinefungal keratitisisolatessusceptibility

Identifiers

PMID31364808
PMCPMC7004187
OpenAlexW2965780864

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.