ArticleCerebral cortex (New York, N.Y. : 1991)2020
Uncovering a Role for the Dorsal Hippocampal Commissure in Recognition Memory.
Article in Cerebral cortex (New York, N.Y. : 1991), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
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Who cites it
17 citing papers in PubMed, 23 citations in OpenAlex.
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- Dose-Dependent Dual Effects of Gradient Ionizing Radiation on Neurocognition.International journal of molecular sciences · 2026Review
- Moderating effects of limbic white matter on verbal memory in older adults with multiple sclerosis.Neuropsychology · 2026Article
- FKBP51 in glutamatergic forebrain neurons promotes early life stress inoculation in female mice.Nature communications · 2025Article
- Dialogical Structure of the Brain and the Ternary System of the Mind: The Neurosemiotics of Yuri Lotman.Consortium psychiatricum · 2025Article
- Sex difference in brain functional connectivity of hippocampus in Alzheimer's disease.GeroScience · 2024Article
- Does Ipsilateral Remapping Following Hand Loss Impact Motor Control of the Intact Hand?The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
- Article
- Alcohol-induced damage to the fimbria/fornix reduces hippocampal-prefrontal cortex connection during early abstinence.Acta neuropathologica communications · 2023Article
- Multimodal anatomy of the human forniceal commissure.Communications biology · 2022Article
- Hippocampal Subfields and White Matter Connectivity in Patients with Subclinical Geriatric Depression.Brain sciences · 2022Article
- Leveraging genetic diversity in mice to inform individual differences in brain microstructure and memory.Frontiers in behavioral neuroscience · 2022Article
- The human dorsal hippocampal commissure: Delineating connections across the midline using multi-modal neuroimaging in major depressive disorder.Neuroimage. Reports · 2021Article
- Preliminary Comparison of Subcortical Structures in Elderly Subclinical Depression: Structural Analysis with 3T MRI.Experimental neurobiology · 2021Article
- Loss of Ryanodine Receptor 2 impairs neuronal activity-dependent remodeling of dendritic spines and triggers compensatory neuronal hyperexcitability.Cell death and differentiation · 2020Article
- Hippocampus co-atrophy pattern in dementia deviates from covariance patterns across the lifespan.Brain : a journal of neurology · 2020Article
- White Matter Dissection of the Fetal Brain.Frontiers in neuroanatomy · 2020Article
Corrections and comments
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Authors and funding
10 authors at 4 institutions in 4 countries.
Funding
Abstract
The dorsal hippocampal commissure (DHC) is a white matter tract that provides interhemispheric connections between temporal lobe brain regions. Despite the importance of these regions for learning and memory, there is scant evidence of a role for the DHC in successful memory performance. We used diffusion-weighted magnetic resonance imaging (DW-MRI) and white matter tractography to reconstruct the DHC in both humans (in vivo) and nonhuman primates (ex vivo). Across species, our findings demonstrate a close consistency between the known anatomy and tract reconstructions of the DHC. Anterograde tract-tracer techniques also highlighted the parahippocampal origins of DHC fibers in nonhuman primates. Finally, we derived diffusion tensor MRI metrics from the DHC in a large sample of human subjects to investigate whether interindividual variation in DHC microstructure is predictive of memory performance. The mean diffusivity of the DHC correlated with performance in a standardized recognition memory task, an effect that was not reproduced in a comparison commissure tract-the anterior commissure. These findings highlight a potential role for the DHC in recognition memory, and our tract reconstruction approach has the potential to generate further novel insights into the role of this previously understudied white matter tract in both health and disease.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.