Evidence map›Paper›PMID 31364552›Full record

Observational studyEpidemiology and infection2019

Strongyloides stercoralis infection in San Marino Republic: first epidemiological data from an observational study.

E D Cappella, A C Piscaglia, A Cadioli, S Manoni, R Silva, D Buonfrate

Open access · hybridAbstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in Epidemiology and infection, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 52% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

E D CappellaClinical Pathology and Transfusion Medicine Unit - State Hospital,Istituto per la Sicurezza Sociale (ISS),Via Scialoja 20, 47893 Borgo Maggiore,Republic of San Marino.
A C PiscagliaEndoscopy and Gastroenterology Unit - State Hospital,Istituto per la Sicurezza Sociale (ISS),Via Scialoja 20, 47893 Borgo Maggiore,Republic of San Marino.
A CadioliDepartment of Surgical Pathology and Cytology,Rimini Hospital - AUSL della Romagna,via Settembrini 2, 47900 Rimini,Italy.
S ManoniClinical Pathology and Transfusion Medicine Unit - State Hospital,Istituto per la Sicurezza Sociale (ISS),Via Scialoja 20, 47893 Borgo Maggiore,Republic of San Marino.
R SilvaDepartment of Infectious - Tropical Diseases and Microbiology,IRCCS Sacro Cuore Don Calabria Hospital,Via Sempreboni 5, 37024 Negrar, Verona,Italy.
D BuonfrateDepartment of Infectious - Tropical Diseases and Microbiology,IRCCS Sacro Cuore Don Calabria Hospital,Via Sempreboni 5, 37024 Negrar, Verona,Italy.ORCID 0000-0003-0108-6822
Istituto per la Ricerca Sociale · ITOspedale Sacro Cuore Don Calabria · ITOspedale Infermi di Rimini · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Strongyloides stercoralis is a neglected parasite that can cause death in immunocompromised individuals. There were no data on the epidemiology of S. stercoralis infection in San Marino Republic until two patients (one of whom died) were diagnosed with severe strongyloidiasis (hyperinfection) between September 2016 and March 2017. A serology test for Strongyloides spp. was introduced in routine practice in the laboratory of the State Hospital to test patients considered to be at risk for strongyloidiasis. Between August 2017 and August 2018, of 42 patients tested with serology, two (4.8%) were positive. An additional case was found by gastric biopsy. Two of the positive cases were presumably autochthonous infections (elderly people with no significant travel history), while the other was a probable imported case (young man born in Nigeria and settled in Europe since 2003). Epidemiology of strongyloidiasis in San Marino might be similar to Northern Italy, where a relevant proportion of cases was diagnosed in immigrants (mainly from sub-Saharan Africa) and in elderly Italians with eosinophilia. Screening for strongyloidiasis might be worthwhile in inhabitants of San Marino in the same categories of individuals, particularly those at risk of immune suppression.

Indexed as

AgedAged, 80 and overAnimalsAntibodies, HelminthBiopsyFemaleHistocytochemistryHumansMaleMiddle AgedSan MarinoSeroepidemiologic StudiesStomachStrongyloides stercoralisStrongyloidiasisAntibodies, HelminthNematodesparasitic disease epidemiology and controlstrongyloidiasis

Identifiers

PMID31364552
PMCPMC6624868
OpenAlexW2947917240

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.