Evidence map›Paper›PMID 31364536›Full record

ArticleEpidemiology and infection2019

Attrition during pre-ART and ART time periods among adolescents enrolled in Integrated HIV Care Programme in Myanmar, 2005-2017.

T Htun, K W Y Kyaw, T K Aung, J Moe, A A Mon, C L Tun, O Mon, S Satyanarayana, H N Oo

Abstract read
In one paragraph

Article in Epidemiology and infection, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Treatment Outcomes After Offering Same-Day Initiation of Human Immunodeficiency Virus Treatment-How to Interpret Discrepancies Between Different Studies.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2023
    Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

T HtunInternational Union against Tuberculosis and Lung Disease (The Union),Mandalay,Myanmar.ORCID 0000-0002-0991-4752
K W Y KyawInternational Union against Tuberculosis and Lung Disease (The Union),Mandalay,Myanmar.
T K AungInternational Union against Tuberculosis and Lung Disease (The Union),Mandalay,Myanmar.
J MoeInternational Union against Tuberculosis and Lung Disease (The Union),Mandalay,Myanmar.
A A MonInternational Union against Tuberculosis and Lung Disease (The Union),Mandalay,Myanmar.
C L TunInternational Union against Tuberculosis and Lung Disease (The Union),Mandalay,Myanmar.
O MonDepartment of Paediatrics,University of Medicine,Mandalay,Myanmar.
S SatyanarayanaCentre for Operational Research, International Union against Tuberculosis and Lung disease (The Union),Paris,France.
H N OoDepartment of Public Health,National AIDS Programme, Ministry of Health and Sports,Myanmar.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Retaining adolescents (aged 10-19 years), living with HIV (ALHIV) on antiretroviral therapy (ART) is challenging. In Myanmar, 1269 ALHIV were under an Integrated HIV Care (IHC) Programme by June 2017 and their attrition (death and lost to follow-up) rates were not assessed before. We undertook a cohort study using routinely collected data of ALHIV enrolled into HIV care from July 2005 to June 2017 and assessed their attrition rates in June 2018 by time-to-event analysis. Of 1269 enrolled, 197(16%) and of 1054 initiated ART, 224 (21%) had an attrition defining event. The pre-ART and ART attrition rates were 21.8 (95% CI 19.0-25.1) and 6.4 (95% CI 5.6-7.3) per 100 person-years follow-up, respectively. The factors 'at enrolment' that were associated with higher hazards of attrition were: (1) WHO stage 3 or 4; (2) haemoglobin <10 gm/dl; (3) no documented CD4 cell counts, hepatitis B and C test results; and (4) injection drug use. Baseline hazards were high during the initial 1-2 years and after 5-6 years. The pre-ART and ART attrition rates in ALHIV were lower than those in Africa but higher than the children under IHC. This warrants designing and implementing additional care tailored to the needs of ALHIV under IHC.

Indexed as

Antiretroviral Therapy, Highly ActiveAdolescentAnti-Retroviral AgentsChildCohort StudiesFemaleHIV InfectionsHumansLost to Follow-UpMaleMyanmarSurvival AnalysisTime FactorsAnti-Retroviral AgentsALHIVdeathloss to follow-upLTFUretention

Identifiers

PMID31364536
PMCPMC6624863

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.