Evidence map›Paper›PMID 31364390›Full record

ArticleCancer control : journal of the Moffitt Cancer Center

Role of Baseline Albumin-Bilirubin Grade on Predict Overall Survival Among Sorafenib-Treated Patients With Hepatocellular Carcinoma in Vietnam.

Thi Thu Huong Nguyen, Van Hieu Nguyen, Van Hung Nguyen, Thanh Long Nguyen, Van Quang Le

Abstract read
In one paragraph

Article in Cancer control : journal of the Moffitt Cancer Center. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Scientific Evidence for Cancer Control in Vietnam.Cancer control : journal of the Moffitt Cancer Center
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Thi Thu Huong Nguyen1 Department of Oncology, Hanoi Medical University, Hanoi, Vietnam.
Van Hieu Nguyen1 Department of Oncology, Hanoi Medical University, Hanoi, Vietnam.
Van Hung Nguyen1 Department of Oncology, Hanoi Medical University, Hanoi, Vietnam.
Thanh Long Nguyen1 Department of Oncology, Hanoi Medical University, Hanoi, Vietnam.
Van Quang Le1 Department of Oncology, Hanoi Medical University, Hanoi, Vietnam.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionAlbumin-bilirubin (ALBI) grade has been recently used in evaluation of liver function and prognosis of patients with hepatocellular carcinoma (HCC). However, in Vietnam, the utility of ALBI grade in clinical setting has not been adequately investigated.

methodsThis is a retrospective study of 110 patients with HCC treated with sorafenib from January 2010 to November 2018 at 2 tertiary hospitals in Vietnam. Prognostic value of ALBI grade was evaluated by Kaplan-Meier survival analysis and Cox proportional regression model.

resultsResults showed that the majority of ALBI grade 1 were Child-Pugh level A (97.5%); ALBI grade 2 was seen in all Child-Pugh score groups of 5, 6, 7, ≥8, whereas ALBI grade 3 was mostly reported in Child-Pugh score ≥8 group (83.3%). Compared with ALBI grade 3, ALBI grade 1 reduced 66.4% risk of death (hazards ratio [HR] = 0.336, 95% confidence interval [CI]: 0.115-0.981;

conclusionBaseline ALBI grade is a simple and objective approach in assessing liver functions of patients with HCC. Baseline ALBI grade is an independent predictor of survival in patients treated with sorafenib.

Indexed as

AdultAgedAged, 80 and overAntineoplastic AgentsBilirubinCarcinoma, HepatocellularFemaleHumansKaplan-Meier EstimateLiver NeoplasmsMaleMiddle AgedOutcome Assessment, Health CarePrognosisProportional Hazards ModelsRetrospective StudiesAntineoplastic AgentsBilirubinSerum AlbuminSorafenibalbumin-bilirubin gradehepatocellular carcinomapredict overall survivalsorafenibVietnam

Identifiers

PMID31364390
PMCPMC6669852

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.